The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance

The focus of this eBook is to bring new insights into central immune tolerance. To fulfill that, much has been discussed about the master in the regulation of tolerance, the autoimmune regulator (Aire) gene the main thymus cell type that expresses this gene, the medullary thymic epithelial cells (mT...

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Bibliographic Details

Main Authors:	Geraldo Aleixo Passos, Ernna Herida Oliveira, Daniella Areas Mendes-da-Cruz
Format:	Online
Language:	English
Published:	Frontiers Media SA 2021
Subjects:	R5-920 RC581-607 thymic crosstalk Central Tolerance promiscuous gene expression Aire gene cell-cell interaction thymocyte microRNA Thymic B cell Chemokines Thymus thema EDItEUR::M Medicine and Nursing
Online Access:	18889
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