Mutagenesis

The complexity of problem understanding biochemical and molecular basis of healthy life, and eagerness to find simple solution necessitate evolution of technology like mutagenesis. The chapters of this book contain experiences of scientists working in the area of mutagenesis. It describes suitable e...

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Հրապարակվել է: IntechOpen 2021
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Առցանց հասանելիություն:ONIX_20210420_9789535107071_1532
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collection Directory of Open Access Books
description The complexity of problem understanding biochemical and molecular basis of healthy life, and eagerness to find simple solution necessitate evolution of technology like mutagenesis. The chapters of this book contain experiences of scientists working in the area of mutagenesis. It describes suitable experimental models (microorganism, plants or animals) for testing spontaneous and induced mutations which are useful for basic and translational research. It includes methods towards gene targeting, developing disease and pest resistant plants, creating temperature sensitive molecular machines, understanding mitochondrial mutagenesis, detecting anti-mutagens, improving genetic insight into impaired immunity and disease. It also describes mutagenesis induced by DNA damage. It has also provided advantage of in vitro transcription and translation to yield proteins with point mutations, deletions or insertions for studying stability, DNA-protein or protein-protein interaction. Trust, it will serve readers as valuable integrated resources emphasizing methods of mutagenesis, and understanding mechanism of variable penetrance or expressivity of mutations.
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publishDate 2021
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spelling doab-20.500.12854ir-661742024-04-11T15:10:44Z Mutagenesis Mishra, Rajnikant Genetic engineering thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology The complexity of problem understanding biochemical and molecular basis of healthy life, and eagerness to find simple solution necessitate evolution of technology like mutagenesis. The chapters of this book contain experiences of scientists working in the area of mutagenesis. It describes suitable experimental models (microorganism, plants or animals) for testing spontaneous and induced mutations which are useful for basic and translational research. It includes methods towards gene targeting, developing disease and pest resistant plants, creating temperature sensitive molecular machines, understanding mitochondrial mutagenesis, detecting anti-mutagens, improving genetic insight into impaired immunity and disease. It also describes mutagenesis induced by DNA damage. It has also provided advantage of in vitro transcription and translation to yield proteins with point mutations, deletions or insertions for studying stability, DNA-protein or protein-protein interaction. Trust, it will serve readers as valuable integrated resources emphasizing methods of mutagenesis, and understanding mechanism of variable penetrance or expressivity of mutations. 2021-04-20T15:36:00Z 2021-04-20T15:36:00Z 2012 book ONIX_20210420_9789535107071_1532 9789535107071 9789535153122 https://directory.doabooks.org/handle/20.500.12854/66174 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/2562/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/2937 10.5772/2937 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535107071 9789535153122 IntechOpen 258 open access
spellingShingle Genetic engineering
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
Mutagenesis
title Mutagenesis
title_full Mutagenesis
title_fullStr Mutagenesis
title_full_unstemmed Mutagenesis
title_short Mutagenesis
title_sort mutagenesis
topic Genetic engineering
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
topic_facet Genetic engineering
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
url ONIX_20210420_9789535107071_1532