Proteoforms
A proteoform is the basic unit in a proteome, defined as its amino acid sequence + post-translational modifications + spatial conformation + localization + cofactors + binding partners + a function, which is the final functional performer of a gene. Studies on proteoforms offer in-depth insights and...
में बचाया:
| स्वरूप: | Online |
|---|---|
| भाषा: | अंग्रेज़ी |
| प्रकाशित: |
IntechOpen
2021
|
| विषय: | |
| ऑनलाइन पहुंच: | ONIX_20210420_9781838800345_2958 |
| टैग: |
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
|
| _version_ | 1869524179778273280 |
|---|---|
| collection | Directory of Open Access Books |
| description | A proteoform is the basic unit in a proteome, defined as its amino acid sequence + post-translational modifications + spatial conformation + localization + cofactors + binding partners + a function, which is the final functional performer of a gene. Studies on proteoforms offer in-depth insights and can lead to the discovery of reliable biomarkers and therapeutic targets for effective prediction, diagnosis, prognostic assessment, and therapy of disease. This book focuses on the concept, study, and applications of proteoforms. Chapters cover such topics as methodologies for identifying and preparing proteoforms, proteoform pattern alteration in pituitary adenomas, and proteoforms in leukemia. |
| format | Online |
| id | doab-20.500.12854ir-67598 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-675982024-04-05T17:30:53Z Proteoforms Zhan, Xianquan Proteins thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry A proteoform is the basic unit in a proteome, defined as its amino acid sequence + post-translational modifications + spatial conformation + localization + cofactors + binding partners + a function, which is the final functional performer of a gene. Studies on proteoforms offer in-depth insights and can lead to the discovery of reliable biomarkers and therapeutic targets for effective prediction, diagnosis, prognostic assessment, and therapy of disease. This book focuses on the concept, study, and applications of proteoforms. Chapters cover such topics as methodologies for identifying and preparing proteoforms, proteoform pattern alteration in pituitary adenomas, and proteoforms in leukemia. 2021-04-20T16:19:19Z 2021-04-20T16:19:19Z 2020 book ONIX_20210420_9781838800345_2958 9781838800345 9781838800338 9781839628320 https://directory.doabooks.org/handle/20.500.12854/67598 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/9352/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.83687 10.5772/intechopen.83687 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781838800345 9781838800338 9781839628320 IntechOpen 90 open access |
| spellingShingle | Proteins thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry Proteoforms |
| title | Proteoforms |
| title_full | Proteoforms |
| title_fullStr | Proteoforms |
| title_full_unstemmed | Proteoforms |
| title_short | Proteoforms |
| title_sort | proteoforms |
| topic | Proteins thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| topic_facet | Proteins thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| url | ONIX_20210420_9781838800345_2958 |