Asthma

Asthma is a common complex and heterogeneous respiratory disease with an increasing prevalence in developed countries. Asthma is a disease consisting of different phenotypes that are driven by different mechanistic pathways (endotypes). The recognition of these phenotypes and endotypes is central to...

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Natura:	Online
Lingua:	inglese
Pubblicazione:	MDPI - Multidisciplinary Digital Publishing Institute 2021
Soggetti:	asthma lactic acidosis hyperchloremic acidosis hypocapnia hypercapnia wheezing bronchial biopsies symptom persistence clinical remission eosinophil adhesion viability proliferation airway smooth muscle cell pulmonary fibroblast phenotype acute severe asthma exacerbation near fatal asthma severe asthma inflammation interleukin-5 (IL-5) anti-IL-5 interleukin-4 airway remodeling matrix metalloproteinases-9 tissue inhibitor of metalloproteinase-1 alveolar macrophages lung function bronchodilation resistance obstruction reproducible spirometry obstructive sleep apnea bronchial asthma alternative overlap syndrome exacerbation reactive oxygen species PBMC mitochondrial function innate immunity immune regulation NLRP3 IL-1β allergic airway inflammation microbiome pathogenesis immune responses PreDicta preschool FeNO asthma-specific quality of life chronic rhinitis disease-specific quality of life health-related quality of Life (HRQLQ) children longitudinal study thema EDItEUR::M Medicine and Nursing
Accesso online:	ONIX_20210501_9783039438594_22
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Asthma

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