The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease
Recent biochemical studies indicate that calorie restriction (CR) is a widely accepted method for anti-aging intervention. CR and intermittent fasting (IF), which involves reduced calories but proper nutritional intake during specific periods, are interventions that can consistently promote health b...
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| Aineistotyyppi: | Online |
|---|---|
| Kieli: | englanti |
| Julkaistu: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Aiheet: | |
| Linkit: | ONIX_20210501_9783039438372_101 |
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| _version_ | 1869520583586217984 |
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| collection | Directory of Open Access Books |
| description | Recent biochemical studies indicate that calorie restriction (CR) is a widely accepted method for anti-aging intervention. CR and intermittent fasting (IF), which involves reduced calories but proper nutritional intake during specific periods, are interventions that can consistently promote health benefits, delay biological aging, and extend both average and maximal lifespan. Furthermore, CR can modulate age-related diseases such as Alzheimer’s disease, atherosclerosis, diabetes, obesity, cancer, and others. Advances in omics technologies have provided a technical breakthrough that enabled the investigation of DNA, RNA, proteins, and other cellular molecules and their comprehensive interactions in a biological context. Nowadays, it is possible to analyze and integrate biological processes that occur in aging systems at the molecular level using state-of-the-art techniques such as next-generation sequencing (NGS), proteomics, lipidomics, metabolomics, and epigenomics. Omics technology and systems gerontology provide predictive information on CR effects, molecular mechanisms, and pathways underlying the anti-aging actions of CR and IF. This Special Issue, “The effects of calorie restriction and intermittent fasting on health and disease”, focuses on the effects of calorie restriction and intermittent fasting on age-related inflammation, autophagy, metabolism, longevity, mitochondrial function, and age-related diseases. |
| format | Online |
| id | doab-20.500.12854ir-68356 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-683562024-03-28T03:30:49Z The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease Chung, Hae-Young calorie restriction diet body mass reduction insulin IGF-1 leptin adiponectin malnutrition heart impairment papillary muscle assay calcium transient proteins SERCA2a L-type calcium channel aging autophagy calorie restriction (CR) CR mimetic calorie restriction FoxO transcription factor sirtuin neuropeptide Y pleiotropy of CR genes senescence-associated secretory phenotype senoinflammation mimetics intermittent fasting fat mass insulin secretion pancreatic islet lifespan longevity fasting skin aging photoaging skin appendages caloric restriction fatty acid biosynthesis mitochondrial biogenesis adipocyte n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society Recent biochemical studies indicate that calorie restriction (CR) is a widely accepted method for anti-aging intervention. CR and intermittent fasting (IF), which involves reduced calories but proper nutritional intake during specific periods, are interventions that can consistently promote health benefits, delay biological aging, and extend both average and maximal lifespan. Furthermore, CR can modulate age-related diseases such as Alzheimer’s disease, atherosclerosis, diabetes, obesity, cancer, and others. Advances in omics technologies have provided a technical breakthrough that enabled the investigation of DNA, RNA, proteins, and other cellular molecules and their comprehensive interactions in a biological context. Nowadays, it is possible to analyze and integrate biological processes that occur in aging systems at the molecular level using state-of-the-art techniques such as next-generation sequencing (NGS), proteomics, lipidomics, metabolomics, and epigenomics. Omics technology and systems gerontology provide predictive information on CR effects, molecular mechanisms, and pathways underlying the anti-aging actions of CR and IF. This Special Issue, “The effects of calorie restriction and intermittent fasting on health and disease”, focuses on the effects of calorie restriction and intermittent fasting on age-related inflammation, autophagy, metabolism, longevity, mitochondrial function, and age-related diseases. 2021-05-01T15:08:01Z 2021-05-01T15:08:01Z 2021 book ONIX_20210501_9783039438372_101 9783039438372 9783039438389 https://directory.doabooks.org/handle/20.500.12854/68356 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3365 https://mdpi.com/books/pdfview/book/3365 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-838-9 10.3390/books978-3-03943-838-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039438372 9783039438389 186 Basel, Switzerland open access |
| spellingShingle | calorie restriction diet body mass reduction insulin IGF-1 leptin adiponectin malnutrition heart impairment papillary muscle assay calcium transient proteins SERCA2a L-type calcium channel aging autophagy calorie restriction (CR) CR mimetic calorie restriction FoxO transcription factor sirtuin neuropeptide Y pleiotropy of CR genes senescence-associated secretory phenotype senoinflammation mimetics intermittent fasting fat mass insulin secretion pancreatic islet lifespan longevity fasting skin aging photoaging skin appendages caloric restriction fatty acid biosynthesis mitochondrial biogenesis adipocyte n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease |
| title | The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease |
| title_full | The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease |
| title_fullStr | The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease |
| title_full_unstemmed | The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease |
| title_short | The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease |
| title_sort | effect of calorie restriction and intermittent fasting on health and disease |
| topic | calorie restriction diet body mass reduction insulin IGF-1 leptin adiponectin malnutrition heart impairment papillary muscle assay calcium transient proteins SERCA2a L-type calcium channel aging autophagy calorie restriction (CR) CR mimetic calorie restriction FoxO transcription factor sirtuin neuropeptide Y pleiotropy of CR genes senescence-associated secretory phenotype senoinflammation mimetics intermittent fasting fat mass insulin secretion pancreatic islet lifespan longevity fasting skin aging photoaging skin appendages caloric restriction fatty acid biosynthesis mitochondrial biogenesis adipocyte n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society |
| topic_facet | calorie restriction diet body mass reduction insulin IGF-1 leptin adiponectin malnutrition heart impairment papillary muscle assay calcium transient proteins SERCA2a L-type calcium channel aging autophagy calorie restriction (CR) CR mimetic calorie restriction FoxO transcription factor sirtuin neuropeptide Y pleiotropy of CR genes senescence-associated secretory phenotype senoinflammation mimetics intermittent fasting fat mass insulin secretion pancreatic islet lifespan longevity fasting skin aging photoaging skin appendages caloric restriction fatty acid biosynthesis mitochondrial biogenesis adipocyte n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society |
| url | ONIX_20210501_9783039438372_101 |