Membrane–Peptide Interactions

This book summarizes the importance of peptide–membrane interactions, mostly aiming at developing new therapeutic approaches. The experimental and computational methodologies used to investigate such interactions reveal the evolution of existing biophysical methodologies, shedding some light on pote...

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Bibliografische gegevens
Formaat:	Online
Taal:	Engels
Gepubliceerd in:	MDPI - Multidisciplinary Digital Publishing Institute 2021
Onderwerpen:	tachyplesin host defense peptide anticancer antimicrobial antibiofilm peptide-membrane interaction structure-activity model membranes nuclear magnetic resonance solution structure accelerated molecular dynamics alamethicin membrane peptaibol cell-penetrating peptide peptide–lipid interaction lipid model systems molecular dynamics NMR membrane biophysics antimicrobial peptides non-lytic peptides bacterial membranes calcium hydroxide chemokine human beta defensin-3-C15 human dental pulp cell Streptococcus gordonii lipoprotein luffa sponge phosphopeptide mass spectrometry Matrix-assisted laser desorption ionization solid-phase extraction surface plasmon resonance melittin liposomes peptide–lipid interactions anti-microbial peptides pore-forming peptides ESKAPE pathogens Staphylococcus aureus KR12 LL-37 lipopeptide critical aggregation concentration CD spectroscopy biofilm cytotoxicity organisms sequence analysis machine learning feature selection sesame protein ACE inhibitory peptides simulated gastrointestinal digestion amino acid sequence molecular docking chionodracines circular dichroism membrane affinity cell-penetrating peptides circular dichroism spectroscopy atomic force microscopy mycolic acid Langmuir monolayer drug–peptide conjugates metastasis model of B16F10 melanoma Pisum sativum defensin 1 (Psd1) anti-metastatic activity glucosylceramide (GlcCer) cyclin F anti-inflammatory peptide cell permeable peptide heparin-binding peptide collagen-induced arthritis inducible nitric oxide interferon gamma interleukin-6 Enbrel thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Online toegang:	ONIX_20210501_9783039430222_834
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Samenvatting:	This book summarizes the importance of peptide–membrane interactions, mostly aiming at developing new therapeutic approaches. The experimental and computational methodologies used to investigate such interactions reveal the evolution of existing biophysical methodologies, shedding some light on potential applications of peptides, as well as on the improvement of their design. Understanding the determinants for peptide–membrane interactions may also improve the knowledge of membrane functions such as the membrane transport, fusion, and signaling processes, contributing to the development of new agents for highly relevant applications ranging from disease treatment to food technology.

Membrane–Peptide Interactions

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