Membrane–Peptide Interactions
This book summarizes the importance of peptide–membrane interactions, mostly aiming at developing new therapeutic approaches. The experimental and computational methodologies used to investigate such interactions reveal the evolution of existing biophysical methodologies, shedding some light on pote...
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| Формат: | Online |
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| Язык: | английский |
| Опубликовано: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Предметы: | |
| Online-ссылка: | ONIX_20210501_9783039430222_834 |
| Метки: |
Нет меток, Требуется 1-ая метка записи!
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| _version_ | 1869518742307733504 |
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| collection | Directory of Open Access Books |
| description | This book summarizes the importance of peptide–membrane interactions, mostly aiming at developing new therapeutic approaches. The experimental and computational methodologies used to investigate such interactions reveal the evolution of existing biophysical methodologies, shedding some light on potential applications of peptides, as well as on the improvement of their design. Understanding the determinants for peptide–membrane interactions may also improve the knowledge of membrane functions such as the membrane transport, fusion, and signaling processes, contributing to the development of new agents for highly relevant applications ranging from disease treatment to food technology. |
| format | Online |
| id | doab-20.500.12854ir-69088 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-690882024-03-28T03:33:24Z Membrane–Peptide Interactions Santos, Nuno C. Gonçalves, Sónia tachyplesin host defense peptide anticancer antimicrobial antibiofilm peptide-membrane interaction structure-activity model membranes nuclear magnetic resonance solution structure accelerated molecular dynamics alamethicin membrane peptaibol cell-penetrating peptide peptide–lipid interaction lipid model systems molecular dynamics NMR membrane biophysics antimicrobial peptides non-lytic peptides bacterial membranes calcium hydroxide chemokine human beta defensin-3-C15 human dental pulp cell Streptococcus gordonii lipoprotein luffa sponge phosphopeptide mass spectrometry Matrix-assisted laser desorption ionization solid-phase extraction surface plasmon resonance melittin liposomes peptide–lipid interactions anti-microbial peptides pore-forming peptides ESKAPE pathogens Staphylococcus aureus KR12 LL-37 lipopeptide critical aggregation concentration CD spectroscopy biofilm cytotoxicity organisms sequence analysis machine learning feature selection sesame protein ACE inhibitory peptides simulated gastrointestinal digestion amino acid sequence molecular docking chionodracines circular dichroism membrane affinity cell-penetrating peptides circular dichroism spectroscopy atomic force microscopy mycolic acid Langmuir monolayer drug–peptide conjugates metastasis model of B16F10 melanoma Pisum sativum defensin 1 (Psd1) anti-metastatic activity glucosylceramide (GlcCer) cyclin F anti-inflammatory peptide cell permeable peptide heparin-binding peptide collagen-induced arthritis inducible nitric oxide interferon gamma interleukin-6 Enbrel thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This book summarizes the importance of peptide–membrane interactions, mostly aiming at developing new therapeutic approaches. The experimental and computational methodologies used to investigate such interactions reveal the evolution of existing biophysical methodologies, shedding some light on potential applications of peptides, as well as on the improvement of their design. Understanding the determinants for peptide–membrane interactions may also improve the knowledge of membrane functions such as the membrane transport, fusion, and signaling processes, contributing to the development of new agents for highly relevant applications ranging from disease treatment to food technology. 2021-05-01T15:40:51Z 2021-05-01T15:40:51Z 2020 book ONIX_20210501_9783039430222_834 9783039430222 9783039430239 https://directory.doabooks.org/handle/20.500.12854/69088 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2857 https://mdpi.com/books/pdfview/book/2857 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-023-9 10.3390/books978-3-03943-023-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039430222 9783039430239 302 Basel, Switzerland open access |
| spellingShingle | tachyplesin host defense peptide anticancer antimicrobial antibiofilm peptide-membrane interaction structure-activity model membranes nuclear magnetic resonance solution structure accelerated molecular dynamics alamethicin membrane peptaibol cell-penetrating peptide peptide–lipid interaction lipid model systems molecular dynamics NMR membrane biophysics antimicrobial peptides non-lytic peptides bacterial membranes calcium hydroxide chemokine human beta defensin-3-C15 human dental pulp cell Streptococcus gordonii lipoprotein luffa sponge phosphopeptide mass spectrometry Matrix-assisted laser desorption ionization solid-phase extraction surface plasmon resonance melittin liposomes peptide–lipid interactions anti-microbial peptides pore-forming peptides ESKAPE pathogens Staphylococcus aureus KR12 LL-37 lipopeptide critical aggregation concentration CD spectroscopy biofilm cytotoxicity organisms sequence analysis machine learning feature selection sesame protein ACE inhibitory peptides simulated gastrointestinal digestion amino acid sequence molecular docking chionodracines circular dichroism membrane affinity cell-penetrating peptides circular dichroism spectroscopy atomic force microscopy mycolic acid Langmuir monolayer drug–peptide conjugates metastasis model of B16F10 melanoma Pisum sativum defensin 1 (Psd1) anti-metastatic activity glucosylceramide (GlcCer) cyclin F anti-inflammatory peptide cell permeable peptide heparin-binding peptide collagen-induced arthritis inducible nitric oxide interferon gamma interleukin-6 Enbrel thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Membrane–Peptide Interactions |
| title | Membrane–Peptide Interactions |
| title_full | Membrane–Peptide Interactions |
| title_fullStr | Membrane–Peptide Interactions |
| title_full_unstemmed | Membrane–Peptide Interactions |
| title_short | Membrane–Peptide Interactions |
| title_sort | membrane peptide interactions |
| topic | tachyplesin host defense peptide anticancer antimicrobial antibiofilm peptide-membrane interaction structure-activity model membranes nuclear magnetic resonance solution structure accelerated molecular dynamics alamethicin membrane peptaibol cell-penetrating peptide peptide–lipid interaction lipid model systems molecular dynamics NMR membrane biophysics antimicrobial peptides non-lytic peptides bacterial membranes calcium hydroxide chemokine human beta defensin-3-C15 human dental pulp cell Streptococcus gordonii lipoprotein luffa sponge phosphopeptide mass spectrometry Matrix-assisted laser desorption ionization solid-phase extraction surface plasmon resonance melittin liposomes peptide–lipid interactions anti-microbial peptides pore-forming peptides ESKAPE pathogens Staphylococcus aureus KR12 LL-37 lipopeptide critical aggregation concentration CD spectroscopy biofilm cytotoxicity organisms sequence analysis machine learning feature selection sesame protein ACE inhibitory peptides simulated gastrointestinal digestion amino acid sequence molecular docking chionodracines circular dichroism membrane affinity cell-penetrating peptides circular dichroism spectroscopy atomic force microscopy mycolic acid Langmuir monolayer drug–peptide conjugates metastasis model of B16F10 melanoma Pisum sativum defensin 1 (Psd1) anti-metastatic activity glucosylceramide (GlcCer) cyclin F anti-inflammatory peptide cell permeable peptide heparin-binding peptide collagen-induced arthritis inducible nitric oxide interferon gamma interleukin-6 Enbrel thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | tachyplesin host defense peptide anticancer antimicrobial antibiofilm peptide-membrane interaction structure-activity model membranes nuclear magnetic resonance solution structure accelerated molecular dynamics alamethicin membrane peptaibol cell-penetrating peptide peptide–lipid interaction lipid model systems molecular dynamics NMR membrane biophysics antimicrobial peptides non-lytic peptides bacterial membranes calcium hydroxide chemokine human beta defensin-3-C15 human dental pulp cell Streptococcus gordonii lipoprotein luffa sponge phosphopeptide mass spectrometry Matrix-assisted laser desorption ionization solid-phase extraction surface plasmon resonance melittin liposomes peptide–lipid interactions anti-microbial peptides pore-forming peptides ESKAPE pathogens Staphylococcus aureus KR12 LL-37 lipopeptide critical aggregation concentration CD spectroscopy biofilm cytotoxicity organisms sequence analysis machine learning feature selection sesame protein ACE inhibitory peptides simulated gastrointestinal digestion amino acid sequence molecular docking chionodracines circular dichroism membrane affinity cell-penetrating peptides circular dichroism spectroscopy atomic force microscopy mycolic acid Langmuir monolayer drug–peptide conjugates metastasis model of B16F10 melanoma Pisum sativum defensin 1 (Psd1) anti-metastatic activity glucosylceramide (GlcCer) cyclin F anti-inflammatory peptide cell permeable peptide heparin-binding peptide collagen-induced arthritis inducible nitric oxide interferon gamma interleukin-6 Enbrel thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20210501_9783039430222_834 |