Buchumschlag

Cellular and Molecular Mechanisms in Pathogenesis of Multiple Sclerosis

Multiple sclerosis (MS) is one of the most common neurological disorders in young adults. The etiology of MS is not known, but it is generally accepted that it is autoimmune in nature. Our knowledge of the pathogenesis of MS has increased tremendously in the past decade through clinical studies and...

Ausführliche Beschreibung

Gespeichert in:
Format: Online
Sprache:Englisch
Veröffentlicht: MDPI - Multidisciplinary Digital Publishing Institute 2021
Schlagworte:
neutrophils
lymphocytes
NLR
multiple sclerosis
disease activity
inside-out
outside-in
oligodendrocytosis
demyelination
gliosis
histology
top-down proteomics
bioinformatics
mitochondria
CD4+ T cells
memory T cells
autoimmune disease
effector memory T cell
central memory T cell
tissue-resident T cell
experimental autoimmune encephalomyelitis
monocytes
granulocyte-macrophage colony-stimulating factor
S100B
relapsing–remitting experimental autoimmune encephalomyelitis
pentamidine
NG2-glia
progenitors
lineage
in utero electroporation
morphometric analyses
clonal analyses
lesioned brain
sphingosine-1-phosphate receptors
glutamate synaptic dysfunction
microglia
T lymphocytes
experimental autoimmune encephalomyelitis (EAE)
pro-inflammatory cytokines
neuroinflammation
ozanimod
AUY954
A971432
S1P1
S1P5
kynurenine pathway
kynurenic acid
oxidative stress
quinolinic acid
N-acetylserotonin
IDO
NAD+, multiple sclerosis
laquinimod
n/a
thema EDItEUR::M Medicine and Nursing
Online-Zugang:ONIX_20210501_9783039435555_1092
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