Cellular and Molecular Mechanisms in Pathogenesis of Multiple Sclerosis

Multiple sclerosis (MS) is one of the most common neurological disorders in young adults. The etiology of MS is not known, but it is generally accepted that it is autoimmune in nature. Our knowledge of the pathogenesis of MS has increased tremendously in the past decade through clinical studies and...

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Bibliografiske detaljer
Format:	Online
Sprog:	engelsk
Udgivet:	MDPI - Multidisciplinary Digital Publishing Institute 2021
Fag:	neutrophils lymphocytes NLR multiple sclerosis disease activity inside-out outside-in oligodendrocytosis demyelination gliosis histology top-down proteomics bioinformatics mitochondria CD4+ T cells memory T cells autoimmune disease effector memory T cell central memory T cell tissue-resident T cell experimental autoimmune encephalomyelitis monocytes granulocyte-macrophage colony-stimulating factor S100B relapsing–remitting experimental autoimmune encephalomyelitis pentamidine NG2-glia progenitors lineage in utero electroporation morphometric analyses clonal analyses lesioned brain sphingosine-1-phosphate receptors glutamate synaptic dysfunction microglia T lymphocytes experimental autoimmune encephalomyelitis (EAE) pro-inflammatory cytokines neuroinflammation ozanimod AUY954 A971432 S1P1 S1P5 kynurenine pathway kynurenic acid oxidative stress quinolinic acid N-acetylserotonin IDO NAD+, multiple sclerosis laquinimod n/a thema EDItEUR::M Medicine and Nursing
Online adgang:	ONIX_20210501_9783039435555_1092
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Cellular and Molecular Mechanisms in Pathogenesis of Multiple Sclerosis

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