Chapter Preparing Proteoforms of Therapeutic Proteins for Top-Down Mass Spectrometry

A characteristic of many proteoforms, derived from a single gene, is their similarity regarding the composition of atoms, making their analysis very challenging. Many overexpressed recombinant proteins are strongly associated with this problem, especially recombinant therapeutic glycoproteins from l...

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Manylion Llyfryddiaeth

Prif Awduron:	Heikaus, Laura, Schlüter, Hartmut, Nurul Hidayah, Siti, Gaikwad, Manasi
Fformat:	Online
Iaith:	Saesneg
Cyhoeddwyd:	InTechOpen 2021
Pynciau:	proteoforms, top-down mass spectrometry, therapeutic proteins, liquid chromatography, protein purification parameter screening, displacement chromatography thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
Mynediad Ar-lein:	ONIX_20210602_10.5772/intechopen.89644_439
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!