Heparan Sulfate Proteoglycans and Their Endogenous Modifying Enzymes: Cancer Players, Biomarkers and Therapeutic Targets

In recent decades, evidence has accumulated implicating heparan sulfate proteoglycans (HSPGs) in tumor initiation and progression. Ubiquitously present at the cell surface and in the extracellular matrix, HSPGs are composed of a protein core with covalently bound heparan sulfate (HS) chains. They pr...

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Bibliographic Details

Format:	Online
Language:	English
Published:	Frontiers Media SA 2021
Subjects:	heparan sulfate proteoglycan heparanase sulfotransferase glypican cancer therapy thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
Online Access:	ONIX_20211118_9782889636167_890
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