Mycotoxins Study: Toxicology, Identification and Control
This Book of Toxins comprises 11 original contributions and one review. New findings regarding presence of mycotoxins in aromatic and medicinal plants, mango and orange juice, juices, pulps, jams, and beer, from Morocco, Pakistan, and Portugal are reported. In these studies, innovative techniques to...
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| 格式: | Online |
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| 語言: | 英语 |
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MDPI - Multidisciplinary Digital Publishing Institute
2022
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| 在線閱讀: | ONIX_20220111_9783036514161_200 |
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| _version_ | 1869529932999163904 |
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| collection | Directory of Open Access Books |
| description | This Book of Toxins comprises 11 original contributions and one review. New findings regarding presence of mycotoxins in aromatic and medicinal plants, mango and orange juice, juices, pulps, jams, and beer, from Morocco, Pakistan, and Portugal are reported. In these studies, innovative techniques to study their presence has been developed, including liquid chromatography coupled with time-of-flight mass spectrometry to analyse mycotoxins and conjugated mycotoxins. Novel strategies to detect mycotoxin presence and comparisons the characteristics of a rapid quantitative analysis of different mycotoxins (deoxynivalenol, ochratoxin A, patulin, sterigmatocystin, and zearalenone) are also presented using acetyl- and butyrylcholinesterases and photobacterial strains of luminescent cells. Additionally, toxicological effects of zearalenone metabolites and beauvericin on SH-SY5Y neuronal cells are presented. One important point in the control of mycotoxins is related to decontaminated strategies, and in this sense the efficacy of potentially probiotic fruit-derived Lactobacillus isolates in removing aflatoxin M1 (AFM1) is presented. Other mycotoxin decontaminated techniques included in this book are electron beam irradiation (EBI) and degradation of zearalenone and ochratoxin A using ozone. Finally, a review that summarizes the newly discovered macrocyclic trichothecenes and their bioactivities over the last decade is included.The evaluation of the presence of mycotoxins in different matrices is achieved through different analytical tools (including quantitative or qualitative determinations). Studies of mycotoxin isolation, using chromatographyc equipment coupled to spectrometry detectors (QTrap-MS/MS, MS/MS tandem, QTOF-MS/MS), are the most useful tools to control their presence. All these studies represent key steps in the establishment of the limits of detection, limits of quantification, points of identification, accuracy, reproducibility, and repeatability of different procedures. The maximum permitted or recommended levels for mycotoxins in different matrices are within a wide range (including the levels tolerated by infants and animals). In addition, decontaminated strategies, as well as control and evaluation of exposure, are demanded by authorities and food safety systems. |
| format | Online |
| id | doab-20.500.12854ir-76464 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-764642024-03-31T13:10:12Z Mycotoxins Study: Toxicology, Identification and Control Juan García, Cristina patulin mango orange fruit-derived products food safety regulatory limits chitosan mycotoxins detoxification LC-MS/MS optimization Destruxins Bombyx mori BmArgRS BmLamin-C RNA helicase binding protein ozone electron beam irradiation degradation zearalenone ochratoxin A SH-SY5Y cells zearalenone derivates beauvericin MTT qTOF–MS/MS beer immunoaffinity clean-up LC-FD human risk assessment Enniatin B1 biomonitoring in vivo metabolomics high resolution mass spectrometry (HRMS) macrocyclic trichothecenes bioactivities putative biosynthetic pathway macrocycle formation entomopathogens mycoinsecticides secondary metabolites insect pathogenesis acetamiprid accumulation aflatoxin M1 Lactobacillus probiotics binding bioluminescent bacteria immobilized cells cholinesterase-based analysis analytical characteristics enzymatic detoxification co-occurrence Q-TOF-LC/MS exposure Morocco n/a thema EDItEUR::M Medicine and Nursing This Book of Toxins comprises 11 original contributions and one review. New findings regarding presence of mycotoxins in aromatic and medicinal plants, mango and orange juice, juices, pulps, jams, and beer, from Morocco, Pakistan, and Portugal are reported. In these studies, innovative techniques to study their presence has been developed, including liquid chromatography coupled with time-of-flight mass spectrometry to analyse mycotoxins and conjugated mycotoxins. Novel strategies to detect mycotoxin presence and comparisons the characteristics of a rapid quantitative analysis of different mycotoxins (deoxynivalenol, ochratoxin A, patulin, sterigmatocystin, and zearalenone) are also presented using acetyl- and butyrylcholinesterases and photobacterial strains of luminescent cells. Additionally, toxicological effects of zearalenone metabolites and beauvericin on SH-SY5Y neuronal cells are presented. One important point in the control of mycotoxins is related to decontaminated strategies, and in this sense the efficacy of potentially probiotic fruit-derived Lactobacillus isolates in removing aflatoxin M1 (AFM1) is presented. Other mycotoxin decontaminated techniques included in this book are electron beam irradiation (EBI) and degradation of zearalenone and ochratoxin A using ozone. Finally, a review that summarizes the newly discovered macrocyclic trichothecenes and their bioactivities over the last decade is included.The evaluation of the presence of mycotoxins in different matrices is achieved through different analytical tools (including quantitative or qualitative determinations). Studies of mycotoxin isolation, using chromatographyc equipment coupled to spectrometry detectors (QTrap-MS/MS, MS/MS tandem, QTOF-MS/MS), are the most useful tools to control their presence. All these studies represent key steps in the establishment of the limits of detection, limits of quantification, points of identification, accuracy, reproducibility, and repeatability of different procedures. The maximum permitted or recommended levels for mycotoxins in different matrices are within a wide range (including the levels tolerated by infants and animals). In addition, decontaminated strategies, as well as control and evaluation of exposure, are demanded by authorities and food safety systems. 2022-01-11T13:32:39Z 2022-01-11T13:32:39Z 2021 book ONIX_20220111_9783036514161_200 9783036514161 9783036514154 https://directory.doabooks.org/handle/20.500.12854/76464 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/3900 https://mdpi.com/books/pdfview/book/3900 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-1415-4 10.3390/books978-3-0365-1415-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036514161 9783036514154 165 Basel, Switzerland open access |
| spellingShingle | patulin mango orange fruit-derived products food safety regulatory limits chitosan mycotoxins detoxification LC-MS/MS optimization Destruxins Bombyx mori BmArgRS BmLamin-C RNA helicase binding protein ozone electron beam irradiation degradation zearalenone ochratoxin A SH-SY5Y cells zearalenone derivates beauvericin MTT qTOF–MS/MS beer immunoaffinity clean-up LC-FD human risk assessment Enniatin B1 biomonitoring in vivo metabolomics high resolution mass spectrometry (HRMS) macrocyclic trichothecenes bioactivities putative biosynthetic pathway macrocycle formation entomopathogens mycoinsecticides secondary metabolites insect pathogenesis acetamiprid accumulation aflatoxin M1 Lactobacillus probiotics binding bioluminescent bacteria immobilized cells cholinesterase-based analysis analytical characteristics enzymatic detoxification co-occurrence Q-TOF-LC/MS exposure Morocco n/a thema EDItEUR::M Medicine and Nursing Mycotoxins Study: Toxicology, Identification and Control |
| title | Mycotoxins Study: Toxicology, Identification and Control |
| title_full | Mycotoxins Study: Toxicology, Identification and Control |
| title_fullStr | Mycotoxins Study: Toxicology, Identification and Control |
| title_full_unstemmed | Mycotoxins Study: Toxicology, Identification and Control |
| title_short | Mycotoxins Study: Toxicology, Identification and Control |
| title_sort | mycotoxins study toxicology identification and control |
| topic | patulin mango orange fruit-derived products food safety regulatory limits chitosan mycotoxins detoxification LC-MS/MS optimization Destruxins Bombyx mori BmArgRS BmLamin-C RNA helicase binding protein ozone electron beam irradiation degradation zearalenone ochratoxin A SH-SY5Y cells zearalenone derivates beauvericin MTT qTOF–MS/MS beer immunoaffinity clean-up LC-FD human risk assessment Enniatin B1 biomonitoring in vivo metabolomics high resolution mass spectrometry (HRMS) macrocyclic trichothecenes bioactivities putative biosynthetic pathway macrocycle formation entomopathogens mycoinsecticides secondary metabolites insect pathogenesis acetamiprid accumulation aflatoxin M1 Lactobacillus probiotics binding bioluminescent bacteria immobilized cells cholinesterase-based analysis analytical characteristics enzymatic detoxification co-occurrence Q-TOF-LC/MS exposure Morocco n/a thema EDItEUR::M Medicine and Nursing |
| topic_facet | patulin mango orange fruit-derived products food safety regulatory limits chitosan mycotoxins detoxification LC-MS/MS optimization Destruxins Bombyx mori BmArgRS BmLamin-C RNA helicase binding protein ozone electron beam irradiation degradation zearalenone ochratoxin A SH-SY5Y cells zearalenone derivates beauvericin MTT qTOF–MS/MS beer immunoaffinity clean-up LC-FD human risk assessment Enniatin B1 biomonitoring in vivo metabolomics high resolution mass spectrometry (HRMS) macrocyclic trichothecenes bioactivities putative biosynthetic pathway macrocycle formation entomopathogens mycoinsecticides secondary metabolites insect pathogenesis acetamiprid accumulation aflatoxin M1 Lactobacillus probiotics binding bioluminescent bacteria immobilized cells cholinesterase-based analysis analytical characteristics enzymatic detoxification co-occurrence Q-TOF-LC/MS exposure Morocco n/a thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20220111_9783036514161_200 |