Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations

Membrane transporters are of vital importance for cells. They mediate the flux of many substances through the plasma membrane. In this book, the transporters for organic cations, a special class of membrane transporters, are presented. Transporters belonging to this class are important because they...

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Médium:	Online
Jazyk:	angličtina
Vydáno:	MDPI - Multidisciplinary Digital Publishing Institute 2022
Témata:	transporters endogenous metabolism functional subgroups SLC22 remote sensing and signaling drug transporters gut microbiome chronic kidney disease solute carrier 22 (SLC22) Remote Sensing and Signaling Theory interorgan communication organic anion transporter organic cation transporter SLC22A15 SLC22A16 SLC22A18 kidney Malpighian tubule TCGA human pathology atlas gene ontology organic cations transport kidneys regulation Nuclear receptor renal excretion bile acids organic cation transporters drug disposition genetic polymorphisms drug-induced kidney injury nephrotoxicity RA Tofacitinib Baricitinib MATE1 solute carrier (SLC) family OCT1 SLC22A1 species differences drugs pesticides cisplatin nephrotoxicity PPAR-alpha organic transporters serotonin transporter plasma membrane monoamine transporter ketamine isoflurane serotonin clearance antidepressant-like activity chronoamperometry tail suspension test forced swim test hepatotoxicity solute carrier pulmonary drug delivery SLC22A1–5 lung epithelium drug uptake β2-agonists chronic lung diseases anticholinergics trospium OCT MATE drug excretion drug transport n/a thema EDItEUR::M Medicine and Nursing
On-line přístup:	ONIX_20220111_9783036505626_212
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Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations

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