Genome Mining and Synthetic Biology in Marine Natural Products Discovery
In recent years, marine genomics has become a growning rapidly field, helped by the large amount of information that is becoming available to the international scientific community. Taking into account the current excitement in the field of marine biotechnology, this Special Issue entitled “Genome M...
Furkejuvvon:
| Materiálatiipa: | Online |
|---|---|
| Giella: | eaŋgalasgiella |
| Almmustuhtton: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Fáttát: | |
| Liŋkkat: | ONIX_20220111_9783036502540_491 |
| Fáddágilkorat: |
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| _version_ | 1869526116266409984 |
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| collection | Directory of Open Access Books |
| description | In recent years, marine genomics has become a growning rapidly field, helped by the large amount of information that is becoming available to the international scientific community. Taking into account the current excitement in the field of marine biotechnology, this Special Issue entitled “Genome Mining and Synthetic Biology in Marine Natural Product Discovery” aims to to assess the impact of these molecular approaches on the discovery of bioactive compounds from marine organisms. The term “genome mining” is used to identify all bioinformatic investigations aimed at detecting the biosynthetic pathways of bioactive natural products and their possible functional and chemical interactions. Several studies are now reporting on marine organisms. Oceans cover nearly 70% of the Earth’s surface and host a huge ecological, chemical, and biological diversity. The natural conditions of the sea favor, in marine organisms, the production of a large variety of novel molecules with great pharmaceutical potential. Marine organisms are unique in their structural and functional features compared to terrestrial ones. Innovation in this field is very rapid, as revealed by the funding of several Seventh Framework Programme (FP7) and Horizon 2020 projects under the topic “Blue Growth”, with the urgent goal of discovering new drugs. |
| format | Online |
| id | doab-20.500.12854ir-76756 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-767562024-04-09T23:15:31Z Genome Mining and Synthetic Biology in Marine Natural Products Discovery Costantini, Maria genome mining global regulator LaeA overexpression Penicillium dipodomyis sorbicillinoids ulvan-derived oligosaccharides ulvan lyase heterologous expression polysaccharide lyase family 25 whole-genome sequencing docosahexaenoic acid (DHA) polyunsaturated fatty acid fatty acid synthesis pathway polyketide synthase pathway bacteria fungi natural products synthetic biology microalgae monogalactosyldiacylglycerol synthase UDP-sulfoquinovose synthase sulfoquinovosyltransferase monogalactosyldiacylglycerols sulfoquinovosyldiacylglycerols transcriptome analysis n/a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues In recent years, marine genomics has become a growning rapidly field, helped by the large amount of information that is becoming available to the international scientific community. Taking into account the current excitement in the field of marine biotechnology, this Special Issue entitled “Genome Mining and Synthetic Biology in Marine Natural Product Discovery” aims to to assess the impact of these molecular approaches on the discovery of bioactive compounds from marine organisms. The term “genome mining” is used to identify all bioinformatic investigations aimed at detecting the biosynthetic pathways of bioactive natural products and their possible functional and chemical interactions. Several studies are now reporting on marine organisms. Oceans cover nearly 70% of the Earth’s surface and host a huge ecological, chemical, and biological diversity. The natural conditions of the sea favor, in marine organisms, the production of a large variety of novel molecules with great pharmaceutical potential. Marine organisms are unique in their structural and functional features compared to terrestrial ones. Innovation in this field is very rapid, as revealed by the funding of several Seventh Framework Programme (FP7) and Horizon 2020 projects under the topic “Blue Growth”, with the urgent goal of discovering new drugs. 2022-01-11T13:41:06Z 2022-01-11T13:41:06Z 2021 book ONIX_20220111_9783036502540_491 9783036502540 9783036502557 https://directory.doabooks.org/handle/20.500.12854/76756 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/4205 https://mdpi.com/books/pdfview/book/4205 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-0255-7 10.3390/books978-3-0365-0255-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036502540 9783036502557 92 Basel, Switzerland open access |
| spellingShingle | genome mining global regulator LaeA overexpression Penicillium dipodomyis sorbicillinoids ulvan-derived oligosaccharides ulvan lyase heterologous expression polysaccharide lyase family 25 whole-genome sequencing docosahexaenoic acid (DHA) polyunsaturated fatty acid fatty acid synthesis pathway polyketide synthase pathway bacteria fungi natural products synthetic biology microalgae monogalactosyldiacylglycerol synthase UDP-sulfoquinovose synthase sulfoquinovosyltransferase monogalactosyldiacylglycerols sulfoquinovosyldiacylglycerols transcriptome analysis n/a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues Genome Mining and Synthetic Biology in Marine Natural Products Discovery |
| title | Genome Mining and Synthetic Biology in Marine Natural Products Discovery |
| title_full | Genome Mining and Synthetic Biology in Marine Natural Products Discovery |
| title_fullStr | Genome Mining and Synthetic Biology in Marine Natural Products Discovery |
| title_full_unstemmed | Genome Mining and Synthetic Biology in Marine Natural Products Discovery |
| title_short | Genome Mining and Synthetic Biology in Marine Natural Products Discovery |
| title_sort | genome mining and synthetic biology in marine natural products discovery |
| topic | genome mining global regulator LaeA overexpression Penicillium dipodomyis sorbicillinoids ulvan-derived oligosaccharides ulvan lyase heterologous expression polysaccharide lyase family 25 whole-genome sequencing docosahexaenoic acid (DHA) polyunsaturated fatty acid fatty acid synthesis pathway polyketide synthase pathway bacteria fungi natural products synthetic biology microalgae monogalactosyldiacylglycerol synthase UDP-sulfoquinovose synthase sulfoquinovosyltransferase monogalactosyldiacylglycerols sulfoquinovosyldiacylglycerols transcriptome analysis n/a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues |
| topic_facet | genome mining global regulator LaeA overexpression Penicillium dipodomyis sorbicillinoids ulvan-derived oligosaccharides ulvan lyase heterologous expression polysaccharide lyase family 25 whole-genome sequencing docosahexaenoic acid (DHA) polyunsaturated fatty acid fatty acid synthesis pathway polyketide synthase pathway bacteria fungi natural products synthetic biology microalgae monogalactosyldiacylglycerol synthase UDP-sulfoquinovose synthase sulfoquinovosyltransferase monogalactosyldiacylglycerols sulfoquinovosyldiacylglycerols transcriptome analysis n/a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues |
| url | ONIX_20220111_9783036502540_491 |