Plant-Based Bioactive Natural Products: Insights into Molecular Mechanisms of Action
Medicinal plants have been used for the maintenance of human health since ancient times, in the form of food, spices, and traditional medicines. Medicinal plant-based traditional medicines serve as the primary healthcare systems in various countries even in recent times. Alongside this, medicinal pl...
Spremljeno u:
| Format: | Online |
|---|---|
| Jezik: | engleski |
| Izdano: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
|
| Teme: | |
| Online pristup: | ONIX_20220111_9783036524122_802 |
| Oznake: |
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|
| _version_ | 1869519400730624000 |
|---|---|
| collection | Directory of Open Access Books |
| description | Medicinal plants have been used for the maintenance of human health since ancient times, in the form of food, spices, and traditional medicines. Medicinal plant-based traditional medicines serve as the primary healthcare systems in various countries even in recent times. Alongside this, medicinal plants have also served as the one of the main sources for the discovery of new therapeutic agents. At present, various plant extracts and their isolated phytochemicals are screened and evaluated for their diverse pharmacological activities related to both communicable and non-communicable diseases. However, comparatively little focus is given to the detailed mechanism of action of these agents on the molecular level. Molecular mechanism-based studies are essential for the development of evidence-based traditional medicines as well as for the development of isolated natural products as the lead candidates for novel drug discovery. This main focus of this Special Issue “Plant-based Bioactive Natural Products: Insights into Molecular Mechanisms of Action” is to cover the recent advances in science related to the molecular mechanisms of action of natural products. A total of nine articles were published in this Special Issue, including two original research articles and two review articles. This Special Issue has provided some new experimental data on bioactive natural products and their detailed mechanisms of action for biological activities. Similarly, review articles have provided state-of-the-art information on the related topics. I would like to thank all the authors for submitting their manuscripts and the reviewers and editors for their contribution to this Special Issue. Furthermore, I am also grateful to the handling editors and staffs of Applied Sciences for their support during the preparation and finalization of this Special Issue. |
| format | Online |
| id | doab-20.500.12854ir-76970 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-769702024-03-30T23:22:29Z Plant-Based Bioactive Natural Products: Insights into Molecular Mechanisms of Action Devkota, Hari Prasad foodborne diseases giardiasis herbal drugs ethnobotany toxoplasmosis srophularia buergeriana cognitive impairment amyloid beta tau phosphorylation oxidative stress anti-apoptotic Terminalia chebula fruit osteoarthritis AyuFlex® cartilage collapse MMPs inflammation response vascular inflammation liensinine VSMC macrophage proliferation migration Nigella sativa methicillin-resistant Staphylococcus aureus synergism beta-lactam antibiotics artichoke by-products phenolic compounds HPLC-ESI-TOF-MS PLE GRAS Scrophularia buergeriana anti-amnesic effect cholinergic neurotransmission anti-oxidant anti-inflammation Vepris macropylla essential oil citral antiproliferative activity fluorescence and scanning electron microscopy human breast cancer cell line Vaccinium species phytochemicals berry leaf anti-inflammatory pathways endothelial dysfunction natural products bioactive compounds medicinal plants bioactivity mechanism of action traditional medicines thema EDItEUR::M Medicine and Nursing Medicinal plants have been used for the maintenance of human health since ancient times, in the form of food, spices, and traditional medicines. Medicinal plant-based traditional medicines serve as the primary healthcare systems in various countries even in recent times. Alongside this, medicinal plants have also served as the one of the main sources for the discovery of new therapeutic agents. At present, various plant extracts and their isolated phytochemicals are screened and evaluated for their diverse pharmacological activities related to both communicable and non-communicable diseases. However, comparatively little focus is given to the detailed mechanism of action of these agents on the molecular level. Molecular mechanism-based studies are essential for the development of evidence-based traditional medicines as well as for the development of isolated natural products as the lead candidates for novel drug discovery. This main focus of this Special Issue “Plant-based Bioactive Natural Products: Insights into Molecular Mechanisms of Action” is to cover the recent advances in science related to the molecular mechanisms of action of natural products. A total of nine articles were published in this Special Issue, including two original research articles and two review articles. This Special Issue has provided some new experimental data on bioactive natural products and their detailed mechanisms of action for biological activities. Similarly, review articles have provided state-of-the-art information on the related topics. I would like to thank all the authors for submitting their manuscripts and the reviewers and editors for their contribution to this Special Issue. Furthermore, I am also grateful to the handling editors and staffs of Applied Sciences for their support during the preparation and finalization of this Special Issue. 2022-01-11T13:48:00Z 2022-01-11T13:48:00Z 2021 book ONIX_20220111_9783036524122_802 9783036524122 9783036524139 https://directory.doabooks.org/handle/20.500.12854/76970 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/4562 https://mdpi.com/books/pdfview/book/4562 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-2413-9 10.3390/books978-3-0365-2413-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036524122 9783036524139 170 Basel, Switzerland open access |
| spellingShingle | foodborne diseases giardiasis herbal drugs ethnobotany toxoplasmosis srophularia buergeriana cognitive impairment amyloid beta tau phosphorylation oxidative stress anti-apoptotic Terminalia chebula fruit osteoarthritis AyuFlex® cartilage collapse MMPs inflammation response vascular inflammation liensinine VSMC macrophage proliferation migration Nigella sativa methicillin-resistant Staphylococcus aureus synergism beta-lactam antibiotics artichoke by-products phenolic compounds HPLC-ESI-TOF-MS PLE GRAS Scrophularia buergeriana anti-amnesic effect cholinergic neurotransmission anti-oxidant anti-inflammation Vepris macropylla essential oil citral antiproliferative activity fluorescence and scanning electron microscopy human breast cancer cell line Vaccinium species phytochemicals berry leaf anti-inflammatory pathways endothelial dysfunction natural products bioactive compounds medicinal plants bioactivity mechanism of action traditional medicines thema EDItEUR::M Medicine and Nursing Plant-Based Bioactive Natural Products: Insights into Molecular Mechanisms of Action |
| title | Plant-Based Bioactive Natural Products: Insights into Molecular Mechanisms of Action |
| title_full | Plant-Based Bioactive Natural Products: Insights into Molecular Mechanisms of Action |
| title_fullStr | Plant-Based Bioactive Natural Products: Insights into Molecular Mechanisms of Action |
| title_full_unstemmed | Plant-Based Bioactive Natural Products: Insights into Molecular Mechanisms of Action |
| title_short | Plant-Based Bioactive Natural Products: Insights into Molecular Mechanisms of Action |
| title_sort | plant based bioactive natural products insights into molecular mechanisms of action |
| topic | foodborne diseases giardiasis herbal drugs ethnobotany toxoplasmosis srophularia buergeriana cognitive impairment amyloid beta tau phosphorylation oxidative stress anti-apoptotic Terminalia chebula fruit osteoarthritis AyuFlex® cartilage collapse MMPs inflammation response vascular inflammation liensinine VSMC macrophage proliferation migration Nigella sativa methicillin-resistant Staphylococcus aureus synergism beta-lactam antibiotics artichoke by-products phenolic compounds HPLC-ESI-TOF-MS PLE GRAS Scrophularia buergeriana anti-amnesic effect cholinergic neurotransmission anti-oxidant anti-inflammation Vepris macropylla essential oil citral antiproliferative activity fluorescence and scanning electron microscopy human breast cancer cell line Vaccinium species phytochemicals berry leaf anti-inflammatory pathways endothelial dysfunction natural products bioactive compounds medicinal plants bioactivity mechanism of action traditional medicines thema EDItEUR::M Medicine and Nursing |
| topic_facet | foodborne diseases giardiasis herbal drugs ethnobotany toxoplasmosis srophularia buergeriana cognitive impairment amyloid beta tau phosphorylation oxidative stress anti-apoptotic Terminalia chebula fruit osteoarthritis AyuFlex® cartilage collapse MMPs inflammation response vascular inflammation liensinine VSMC macrophage proliferation migration Nigella sativa methicillin-resistant Staphylococcus aureus synergism beta-lactam antibiotics artichoke by-products phenolic compounds HPLC-ESI-TOF-MS PLE GRAS Scrophularia buergeriana anti-amnesic effect cholinergic neurotransmission anti-oxidant anti-inflammation Vepris macropylla essential oil citral antiproliferative activity fluorescence and scanning electron microscopy human breast cancer cell line Vaccinium species phytochemicals berry leaf anti-inflammatory pathways endothelial dysfunction natural products bioactive compounds medicinal plants bioactivity mechanism of action traditional medicines thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20220111_9783036524122_802 |