Modern Approaches in Cardiovascular Disease Therapeutics: From Molecular Genetics to Tissue Engineering
Cardiovascular disease (CVD) currently represents one of the leading causes of death worldwide. Each year, more than 17.9 million people die due to CVD manifestations. To reverse these manifestations, the transplantation of secondary vessels or the use of synthetic vascular grafts represents the gol...
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| Format: | Online |
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| Sprache: | Englisch |
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MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Online-Zugang: | ONIX_20220111_9783036524368_812 |
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| description | Cardiovascular disease (CVD) currently represents one of the leading causes of death worldwide. Each year, more than 17.9 million people die due to CVD manifestations. To reverse these manifestations, the transplantation of secondary vessels or the use of synthetic vascular grafts represents the gold standard procedure. However, significant adverse reactions have been described in the literature regarding the use of these type of grafts. In this regard, modern therapeutic strategies focused on CVD therapeutics must be proposed and evaluated. As alternative therapies, advanced tissue engineering approaches, including decellularization procedures and the 3D additive bio-printing methods, are currently being investigated. In this Special Issue of Bioengineering, we aimed to highlight modern approaches regarding CVD. This Special Issue, entitled “Modern Approaches in Cardiovascular Disease Therapeutics: From Molecular Genetics to Tissue Engineering”, includes 5 articles. These articles are related to the efficient production of small-diameter vascular grafts, vascular graft development with 3D printing approaches, and in vitro models for the improved assessment of atherosclerosis mechanisms. The Guest Editors of this Special Issue wish to express their gratitude to all contributors for their unique and outstanding articles. Additionally, special credit is given to all reviewers for their comprehensive analysis and overall effort in improving the quality of the published articles. |
| format | Online |
| id | doab-20.500.12854ir-76980 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-769802024-03-30T23:22:45Z Modern Approaches in Cardiovascular Disease Therapeutics: From Molecular Genetics to Tissue Engineering Mallis, Panagiotis Michalopoulos, Efstathios atherosclerosis monocyte macrophage disease model collagen 3D cell culture immunomechanobiology small-diameter vascular grafts tissue engineering cardiovascular disease vascular reconstruction bypass surgery decellularization human umbilical arteries synthetic materials 3D and 4D printing thermoresponsive materials mesenchymal stromal cells repopulation Ki67 MAP kinase 3D bioprinting cell therapy 3D printing macrophages thema EDItEUR::M Medicine and Nursing Cardiovascular disease (CVD) currently represents one of the leading causes of death worldwide. Each year, more than 17.9 million people die due to CVD manifestations. To reverse these manifestations, the transplantation of secondary vessels or the use of synthetic vascular grafts represents the gold standard procedure. However, significant adverse reactions have been described in the literature regarding the use of these type of grafts. In this regard, modern therapeutic strategies focused on CVD therapeutics must be proposed and evaluated. As alternative therapies, advanced tissue engineering approaches, including decellularization procedures and the 3D additive bio-printing methods, are currently being investigated. In this Special Issue of Bioengineering, we aimed to highlight modern approaches regarding CVD. This Special Issue, entitled “Modern Approaches in Cardiovascular Disease Therapeutics: From Molecular Genetics to Tissue Engineering”, includes 5 articles. These articles are related to the efficient production of small-diameter vascular grafts, vascular graft development with 3D printing approaches, and in vitro models for the improved assessment of atherosclerosis mechanisms. The Guest Editors of this Special Issue wish to express their gratitude to all contributors for their unique and outstanding articles. Additionally, special credit is given to all reviewers for their comprehensive analysis and overall effort in improving the quality of the published articles. 2022-01-11T13:48:17Z 2022-01-11T13:48:17Z 2021 book ONIX_20220111_9783036524368_812 9783036524368 9783036524375 https://directory.doabooks.org/handle/20.500.12854/76980 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/4573 https://mdpi.com/books/pdfview/book/4573 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-2437-5 10.3390/books978-3-0365-2437-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036524368 9783036524375 112 Basel, Switzerland open access |
| spellingShingle | atherosclerosis monocyte macrophage disease model collagen 3D cell culture immunomechanobiology small-diameter vascular grafts tissue engineering cardiovascular disease vascular reconstruction bypass surgery decellularization human umbilical arteries synthetic materials 3D and 4D printing thermoresponsive materials mesenchymal stromal cells repopulation Ki67 MAP kinase 3D bioprinting cell therapy 3D printing macrophages thema EDItEUR::M Medicine and Nursing Modern Approaches in Cardiovascular Disease Therapeutics: From Molecular Genetics to Tissue Engineering |
| title | Modern Approaches in Cardiovascular Disease Therapeutics: From Molecular Genetics to Tissue Engineering |
| title_full | Modern Approaches in Cardiovascular Disease Therapeutics: From Molecular Genetics to Tissue Engineering |
| title_fullStr | Modern Approaches in Cardiovascular Disease Therapeutics: From Molecular Genetics to Tissue Engineering |
| title_full_unstemmed | Modern Approaches in Cardiovascular Disease Therapeutics: From Molecular Genetics to Tissue Engineering |
| title_short | Modern Approaches in Cardiovascular Disease Therapeutics: From Molecular Genetics to Tissue Engineering |
| title_sort | modern approaches in cardiovascular disease therapeutics from molecular genetics to tissue engineering |
| topic | atherosclerosis monocyte macrophage disease model collagen 3D cell culture immunomechanobiology small-diameter vascular grafts tissue engineering cardiovascular disease vascular reconstruction bypass surgery decellularization human umbilical arteries synthetic materials 3D and 4D printing thermoresponsive materials mesenchymal stromal cells repopulation Ki67 MAP kinase 3D bioprinting cell therapy 3D printing macrophages thema EDItEUR::M Medicine and Nursing |
| topic_facet | atherosclerosis monocyte macrophage disease model collagen 3D cell culture immunomechanobiology small-diameter vascular grafts tissue engineering cardiovascular disease vascular reconstruction bypass surgery decellularization human umbilical arteries synthetic materials 3D and 4D printing thermoresponsive materials mesenchymal stromal cells repopulation Ki67 MAP kinase 3D bioprinting cell therapy 3D printing macrophages thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20220111_9783036524368_812 |