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Biomaterial-Assisted 3D In Vitro Tumor Models: From Organoid towards Cancer Tissue Engineering Approaches

This reprint focuses on fundamental and applied research involving the combination of biomaterials and cancer cells to develop a three-dimensional (3D) tumor microenvironment in vitro, in which carcinogenesis mechanisms can be studied and therapies can be screened. Such models are becoming quite pop...

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Formato: Online
Idioma:inglês
Publicado em: MDPI - Multidisciplinary Digital Publishing Institute 2023
Assuntos:
biomaterials
tissue engineering
3D cell culture
cancer cells
bioprinting
breast cancer
metastasis
bone
3D modeling
tumor microenvironment
extracellular matrix
3D printing
3D bioprinting
bone cancer
calcium phosphates
bone model
orthopedics
EGFR
trafficking
degradation
self-assembling peptides
3D culture
pancreatic ductal adenocarcinoma
PDAC
drug resistance
3D tumor model
3D microfiber
amoeboid cell migration
brain cancer
PTEN
RHO
ROCK
durotaxis
topotaxis
pancreatic cancer
tumour microenvironment (TME)
treatment resistance
radiotherapy
radiation
radioprotection
hypoxia
polyurethane scaffolds
extracellular matrix (ECM)
HIF-1a
PANC-1
organoids
tumour heterogeneity
colorectal neoplasms
clonal evolution
longitudinal imaging
neoplasm recurrence
cell lineage
self-renewal
cell culture techniques
3D cancer models
immunotherapies
tumor escape mechanisms
epithelial ovarian cancer
3D in vitro model
chemotherapy
Cisplatin
spheroids
hydrogels
polymeric scaffolds
A2780
SK-OV-3
fused deposition modeling
cancer tissue engineering
in vitro model
mechanical properties
mesenchymal stromal cell
bone matrix
personalized therapy
scaffold
primary cancer cells
experimental models
screening
3Rs
tumour modelling
polyhydroxyalkanoates (PHAs)
colon cancer
epithelial-mesenchymal transition (EMT)
scaffolds
3D
three-dimensional
model
ovarian
cancer
patient-derived
personalised
n/a
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
Acesso em linha:ONIX_20230405_9783036568423_161
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