Role of TCTP in Cell Biological and Disease Processes
Translationally controlled tumor protein (TCTP), also referred to as HRF or fortilin, is a multifunctional protein, expressed in all eukaryotic organisms from protozoa to humans. TCTP is involved in many basic biological processes, such as cell division, growth, and development. It is therefore not...
Gorde:
| Formatua: | Online |
|---|---|
| Hizkuntza: | ingelesa |
| Argitaratua: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
|
| Gaiak: | |
| Sarrera elektronikoa: | ONIX_20220111_9783036522852_873 |
| Etiketak: |
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|
| _version_ | 1869521709487357952 |
|---|---|
| collection | Directory of Open Access Books |
| description | Translationally controlled tumor protein (TCTP), also referred to as HRF or fortilin, is a multifunctional protein, expressed in all eukaryotic organisms from protozoa to humans. TCTP is involved in many basic biological processes, such as cell division, growth, and development. It is therefore not surprising that dysregulation of TCTP occurs in various disease processes, such as cardiovascular, allergic, and immune disorders. TCTP’s role in cancer-promoting pathways is well- documented, and the protein is considered a potential target for the design of new anti-cancer strategies. Therefore, an understanding of the core biological functions of TCTP, the mechanisms underlying its cellular regulation, and its involvement in disease processes is important. This book provides a current overview on the basic biological functions of TCTP and on its role in promoting a range of disease processes. |
| format | Online |
| id | doab-20.500.12854ir-77041 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-770412024-03-28T03:33:33Z Role of TCTP in Cell Biological and Disease Processes Bommer, Ulrich-Axel Kawakami, Toshiaki Loxosceles brown spider TCTP venom toxin HRF allergy mast cells basophils IgE FcεRI translationally controlled tumor protein (TCTP) apoptosis conditional knockout mice development Nestin-cre neurogenesis neuronal progenitor cells perinatal death proliferation Mmi1 translationally controlled tumor protein autophagy reactive oxygen species rapamycin nitrogen starvation cancer phospho-TCTP DHA T-DM1 HER2-positive breast cancer TCTP (HRF fortilin) growth and development biological stress reactions regulation of protein synthesis regulated protein degradation cardiovascular diseases n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Translationally controlled tumor protein (TCTP), also referred to as HRF or fortilin, is a multifunctional protein, expressed in all eukaryotic organisms from protozoa to humans. TCTP is involved in many basic biological processes, such as cell division, growth, and development. It is therefore not surprising that dysregulation of TCTP occurs in various disease processes, such as cardiovascular, allergic, and immune disorders. TCTP’s role in cancer-promoting pathways is well- documented, and the protein is considered a potential target for the design of new anti-cancer strategies. Therefore, an understanding of the core biological functions of TCTP, the mechanisms underlying its cellular regulation, and its involvement in disease processes is important. This book provides a current overview on the basic biological functions of TCTP and on its role in promoting a range of disease processes. 2022-01-11T13:50:11Z 2022-01-11T13:50:11Z 2021 book ONIX_20220111_9783036522852_873 9783036522852 9783036522869 https://directory.doabooks.org/handle/20.500.12854/77041 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/4651 https://mdpi.com/books/pdfview/book/4651 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-2286-9 10.3390/books978-3-0365-2286-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036522852 9783036522869 150 Basel, Switzerland open access |
| spellingShingle | Loxosceles brown spider TCTP venom toxin HRF allergy mast cells basophils IgE FcεRI translationally controlled tumor protein (TCTP) apoptosis conditional knockout mice development Nestin-cre neurogenesis neuronal progenitor cells perinatal death proliferation Mmi1 translationally controlled tumor protein autophagy reactive oxygen species rapamycin nitrogen starvation cancer phospho-TCTP DHA T-DM1 HER2-positive breast cancer TCTP (HRF fortilin) growth and development biological stress reactions regulation of protein synthesis regulated protein degradation cardiovascular diseases n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Role of TCTP in Cell Biological and Disease Processes |
| title | Role of TCTP in Cell Biological and Disease Processes |
| title_full | Role of TCTP in Cell Biological and Disease Processes |
| title_fullStr | Role of TCTP in Cell Biological and Disease Processes |
| title_full_unstemmed | Role of TCTP in Cell Biological and Disease Processes |
| title_short | Role of TCTP in Cell Biological and Disease Processes |
| title_sort | role of tctp in cell biological and disease processes |
| topic | Loxosceles brown spider TCTP venom toxin HRF allergy mast cells basophils IgE FcεRI translationally controlled tumor protein (TCTP) apoptosis conditional knockout mice development Nestin-cre neurogenesis neuronal progenitor cells perinatal death proliferation Mmi1 translationally controlled tumor protein autophagy reactive oxygen species rapamycin nitrogen starvation cancer phospho-TCTP DHA T-DM1 HER2-positive breast cancer TCTP (HRF fortilin) growth and development biological stress reactions regulation of protein synthesis regulated protein degradation cardiovascular diseases n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | Loxosceles brown spider TCTP venom toxin HRF allergy mast cells basophils IgE FcεRI translationally controlled tumor protein (TCTP) apoptosis conditional knockout mice development Nestin-cre neurogenesis neuronal progenitor cells perinatal death proliferation Mmi1 translationally controlled tumor protein autophagy reactive oxygen species rapamycin nitrogen starvation cancer phospho-TCTP DHA T-DM1 HER2-positive breast cancer TCTP (HRF fortilin) growth and development biological stress reactions regulation of protein synthesis regulated protein degradation cardiovascular diseases n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20220111_9783036522852_873 |