Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life

Malnutrition is becoming a more prominent health problem, with an increasing number of elderly CKD patients being put on dialysis. In addition, the presence of inflammation, sarcopenia/frailty, diabetes, and CVD is a definite and independent risk factor associated with higher mortality in this popul...

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collection Directory of Open Access Books
description Malnutrition is becoming a more prominent health problem, with an increasing number of elderly CKD patients being put on dialysis. In addition, the presence of inflammation, sarcopenia/frailty, diabetes, and CVD is a definite and independent risk factor associated with higher mortality in this population. Although the restriction of protein intake has been recommended to protect eGFR decline, hyperphosphatemia, and hyperkalemia in CKD patients, it might accelerate the loss of skeletal muscle and adipose mass, leading to a poor prognosis. Therefore, flexible responses are considered regarding whether protein restriction should be continued or loosened in pre-dialysis CKD patients. In undernourished elderly patients undergoing hemodialysis, sufficient calorie/protein intake is necessary to counteract the development of sarcopenia/frailty. It is expected that the application of new drugs including phosphate binders and potassium chelators may achieve both a high enough intake and balanced levels of phosphate and potassium. Furthermore, the improvement of deficient micronutrients and poor appetite is also necessary. Comprehensive care is essential for the wellbeing of elderly patients undergoing hemodialysis. The topicof this Special Issue is “Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life”.
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spelling doab-20.500.12854ir-771032024-03-30T23:22:43Z Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life Inaba, Masaaki Mori, Katsuhiko hypertension body weight mortality sodium dialysis malnutrition protein energy wasting (PEW) sarcopenia carnitine carnitine deficiency end-stage kidney disease peritoneal dialysis hemodialysis frailty protein energy wasting hypercatabolism renal rehabilitation exercise sarcopenia and frailty nutritional support protein synthesis muscle physiology physical activity exercise tolerance quality of life skeletal muscle aging chronic kidney disease diabetes CKD-MBD FGF23 aKlotho phosphate-binder zinc cardiovascular disease potassium potassium excretion blood pressure salt CKD fat mass visceral fat subcutaneous fat nutrition body mass index obesity paradox magnetic resonance imaging diffusion tensor imaging arterial spin labeling blood oxygenation level-dependent nutritional status dialysis patients clinical malnutrition older individuals n/a thema EDItEUR::M Medicine and Nursing Malnutrition is becoming a more prominent health problem, with an increasing number of elderly CKD patients being put on dialysis. In addition, the presence of inflammation, sarcopenia/frailty, diabetes, and CVD is a definite and independent risk factor associated with higher mortality in this population. Although the restriction of protein intake has been recommended to protect eGFR decline, hyperphosphatemia, and hyperkalemia in CKD patients, it might accelerate the loss of skeletal muscle and adipose mass, leading to a poor prognosis. Therefore, flexible responses are considered regarding whether protein restriction should be continued or loosened in pre-dialysis CKD patients. In undernourished elderly patients undergoing hemodialysis, sufficient calorie/protein intake is necessary to counteract the development of sarcopenia/frailty. It is expected that the application of new drugs including phosphate binders and potassium chelators may achieve both a high enough intake and balanced levels of phosphate and potassium. Furthermore, the improvement of deficient micronutrients and poor appetite is also necessary. Comprehensive care is essential for the wellbeing of elderly patients undergoing hemodialysis. The topicof this Special Issue is “Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life”. 2022-01-11T13:52:19Z 2022-01-11T13:52:19Z 2021 book ONIX_20220111_9783036523460_935 9783036523460 9783036523453 https://directory.doabooks.org/handle/20.500.12854/77103 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/4722 https://mdpi.com/books/pdfview/book/4722 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-2345-3 10.3390/books978-3-0365-2345-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036523460 9783036523453 208 Basel, Switzerland open access
spellingShingle hypertension
body weight
mortality
sodium
dialysis
malnutrition
protein energy wasting (PEW)
sarcopenia
carnitine
carnitine deficiency
end-stage kidney disease
peritoneal dialysis
hemodialysis
frailty
protein energy wasting
hypercatabolism
renal rehabilitation
exercise
sarcopenia and frailty
nutritional support
protein synthesis
muscle physiology
physical activity
exercise tolerance
quality of life
skeletal muscle
aging
chronic kidney disease
diabetes
CKD-MBD
FGF23
aKlotho
phosphate-binder
zinc
cardiovascular disease
potassium
potassium excretion
blood pressure
salt
CKD
fat mass
visceral fat
subcutaneous fat
nutrition
body mass index
obesity paradox
magnetic resonance imaging
diffusion tensor imaging
arterial spin labeling
blood oxygenation level-dependent
nutritional status
dialysis patients
clinical malnutrition
older individuals
n/a
thema EDItEUR::M Medicine and Nursing
Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life
title Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life
title_full Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life
title_fullStr Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life
title_full_unstemmed Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life
title_short Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life
title_sort extension of healthy life span of dialysis patients in the era of a 100 year life
topic hypertension
body weight
mortality
sodium
dialysis
malnutrition
protein energy wasting (PEW)
sarcopenia
carnitine
carnitine deficiency
end-stage kidney disease
peritoneal dialysis
hemodialysis
frailty
protein energy wasting
hypercatabolism
renal rehabilitation
exercise
sarcopenia and frailty
nutritional support
protein synthesis
muscle physiology
physical activity
exercise tolerance
quality of life
skeletal muscle
aging
chronic kidney disease
diabetes
CKD-MBD
FGF23
aKlotho
phosphate-binder
zinc
cardiovascular disease
potassium
potassium excretion
blood pressure
salt
CKD
fat mass
visceral fat
subcutaneous fat
nutrition
body mass index
obesity paradox
magnetic resonance imaging
diffusion tensor imaging
arterial spin labeling
blood oxygenation level-dependent
nutritional status
dialysis patients
clinical malnutrition
older individuals
n/a
thema EDItEUR::M Medicine and Nursing
topic_facet hypertension
body weight
mortality
sodium
dialysis
malnutrition
protein energy wasting (PEW)
sarcopenia
carnitine
carnitine deficiency
end-stage kidney disease
peritoneal dialysis
hemodialysis
frailty
protein energy wasting
hypercatabolism
renal rehabilitation
exercise
sarcopenia and frailty
nutritional support
protein synthesis
muscle physiology
physical activity
exercise tolerance
quality of life
skeletal muscle
aging
chronic kidney disease
diabetes
CKD-MBD
FGF23
aKlotho
phosphate-binder
zinc
cardiovascular disease
potassium
potassium excretion
blood pressure
salt
CKD
fat mass
visceral fat
subcutaneous fat
nutrition
body mass index
obesity paradox
magnetic resonance imaging
diffusion tensor imaging
arterial spin labeling
blood oxygenation level-dependent
nutritional status
dialysis patients
clinical malnutrition
older individuals
n/a
thema EDItEUR::M Medicine and Nursing
url ONIX_20220111_9783036523460_935