Special Issue in Honor of Professor James D. McChesney on the Occasion of his 80th Birthday
Plants have been the sources of important pharmaceuticals, flavoring agents, and agrochemicals. The antimalarial drugs artemisinin and quinine; the anticancer drugs taxol, etoposide, and vinca alkaloids; the sugar-free sweetening agents stevioside and rebaudiosides; and antifeedant azadiractin are g...
সংরক্ষণ করুন:
| বিন্যাস: | Online |
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| ভাষা: | ইংরেজি |
| প্রকাশিত: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | ONIX_20220224_9783036527130_112 |
| ট্যাগগুলো: |
কোনো ট্যাগ নেই, প্রথমজন হিসাবে ট্যাগ করুন!
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| _version_ | 1869529452018401280 |
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| collection | Directory of Open Access Books |
| description | Plants have been the sources of important pharmaceuticals, flavoring agents, and agrochemicals. The antimalarial drugs artemisinin and quinine; the anticancer drugs taxol, etoposide, and vinca alkaloids; the sugar-free sweetening agents stevioside and rebaudiosides; and antifeedant azadiractin are good examples of important plant-based drugs, food additives, and agrochemicals currently on the market. Despite these and many other successes, there are significant challenges to discovering and developing commercially important natural products from plants, such as procuring plant materials in large quantities, separating active constituents from complex mixtures, and undesirable qualities, such as low solubility or poor chemical or metabolic stability of active constituents. Dr. James D. McChesney has contributed immensely to overcoming the inherent challenges associated with discovering and developing products modeled from plant-based natural product leads. His research on artemisinin, taxol, galanthamine, podophyllotoxin, and stevia sweet glycosides exemplifies the magnitude of these contributions. His extensive work on the structural modification of taxol led to the discovery and development of the anticancer agent TPI 287, a third-generation taxane analog that is currently undergoing clinical trials. Dr. McChesney has had a long, distinguished teaching and research career, has authored more than 225 research publications, and holds more than 60 patents. He is a past president and Fellow of the American Society of Pharmacognosy and a Fellow of the AAAS. He has mentored many graduate students, post-docs, and junior faculty members who hold prominent positions in natural products research establishments in the US and worldwide. We wish to dedicate this Special Issue Book Version to celebrate the eightieth birthday of Dr. McChesney, a prolific thinker with abundant inventiveness in the field of natural product chemistry and pharmacognosy. |
| format | Online |
| id | doab-20.500.12854ir-78814 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-788142024-03-28T03:33:55Z Special Issue in Honor of Professor James D. McChesney on the Occasion of his 80th Birthday Ilias, Muhammad Nanayakkara, Dhammika Magnoliaceae GC-FID GC-MS mosquito control 1-decanol 1-octanol larvicidal activity deterrent biopesticides Persea americana Mill. avocado oil triglyceride fatty acid UHPLC/ESI-MS GC/MS quality evaluation Calu-3 cell line cancer chemotherapy drug resistance poly(ε-caprolactone) poly(ethylene glycol) isoflavonoids polyisoprenylated benzophenones propolis botanical sources oxyresveratrol Artocarpus lakoocha DNA damaging pro-oxidant medicinal plants cancer Ethiopia phytochemistry endophytic fungus Teratosphaeria teratopyrones naphtho-γ-pyrones nigerasperone A recombinant monoamine oxidase-A monoamine oxidase-B neurological disorder enzyme kinetics molecular docking inhibition activity flavonoid Atractylodes macrocephala wheat bran processing NMR atractylon derivatives isolation and identification Machaerium Rimachi 12161 machaerifurogerol 5-epi-machaerifurogerol machaeriol A–C machaeridiol A–C isoflavonoid MRSA VRE gram negative bacteria Torreya taxifolia plant pathogenic fungi Botryosphaeria dothidea malaria phytotoxin γ-lactam alkaloids Momordica charantia cucurbitane-type triterpene glycosides charantoside XV α-amylase α-glucosidase anti-inflammatory activity in silico study in vitro propagation medicinal crops phytomedicines Stevia rebaudiana HPTLC HPLC methods mass spectrometry dissociation pattern endocyclic and exocyclic diterpene glycosides scale up UHPLC/Q-TOF-MS analysis glycerin process contaminants 3-monochloropropane-1,2-diol esters glycidyl esters glycyrrhizin SARS-CoV-2 surface plasmon resonance autodocking n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Plants have been the sources of important pharmaceuticals, flavoring agents, and agrochemicals. The antimalarial drugs artemisinin and quinine; the anticancer drugs taxol, etoposide, and vinca alkaloids; the sugar-free sweetening agents stevioside and rebaudiosides; and antifeedant azadiractin are good examples of important plant-based drugs, food additives, and agrochemicals currently on the market. Despite these and many other successes, there are significant challenges to discovering and developing commercially important natural products from plants, such as procuring plant materials in large quantities, separating active constituents from complex mixtures, and undesirable qualities, such as low solubility or poor chemical or metabolic stability of active constituents. Dr. James D. McChesney has contributed immensely to overcoming the inherent challenges associated with discovering and developing products modeled from plant-based natural product leads. His research on artemisinin, taxol, galanthamine, podophyllotoxin, and stevia sweet glycosides exemplifies the magnitude of these contributions. His extensive work on the structural modification of taxol led to the discovery and development of the anticancer agent TPI 287, a third-generation taxane analog that is currently undergoing clinical trials. Dr. McChesney has had a long, distinguished teaching and research career, has authored more than 225 research publications, and holds more than 60 patents. He is a past president and Fellow of the American Society of Pharmacognosy and a Fellow of the AAAS. He has mentored many graduate students, post-docs, and junior faculty members who hold prominent positions in natural products research establishments in the US and worldwide. We wish to dedicate this Special Issue Book Version to celebrate the eightieth birthday of Dr. McChesney, a prolific thinker with abundant inventiveness in the field of natural product chemistry and pharmacognosy. 2022-02-24T10:37:25Z 2022-02-24T10:37:25Z 2022 book ONIX_20220224_9783036527130_112 9783036527130 9783036527123 https://directory.doabooks.org/handle/20.500.12854/78814 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/4909 https://mdpi.com/books/pdfview/book/4909 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-2713-0 10.3390/books978-3-0365-2713-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036527130 9783036527123 262 Basel open access |
| spellingShingle | Magnoliaceae GC-FID GC-MS mosquito control 1-decanol 1-octanol larvicidal activity deterrent biopesticides Persea americana Mill. avocado oil triglyceride fatty acid UHPLC/ESI-MS GC/MS quality evaluation Calu-3 cell line cancer chemotherapy drug resistance poly(ε-caprolactone) poly(ethylene glycol) isoflavonoids polyisoprenylated benzophenones propolis botanical sources oxyresveratrol Artocarpus lakoocha DNA damaging pro-oxidant medicinal plants cancer Ethiopia phytochemistry endophytic fungus Teratosphaeria teratopyrones naphtho-γ-pyrones nigerasperone A recombinant monoamine oxidase-A monoamine oxidase-B neurological disorder enzyme kinetics molecular docking inhibition activity flavonoid Atractylodes macrocephala wheat bran processing NMR atractylon derivatives isolation and identification Machaerium Rimachi 12161 machaerifurogerol 5-epi-machaerifurogerol machaeriol A–C machaeridiol A–C isoflavonoid MRSA VRE gram negative bacteria Torreya taxifolia plant pathogenic fungi Botryosphaeria dothidea malaria phytotoxin γ-lactam alkaloids Momordica charantia cucurbitane-type triterpene glycosides charantoside XV α-amylase α-glucosidase anti-inflammatory activity in silico study in vitro propagation medicinal crops phytomedicines Stevia rebaudiana HPTLC HPLC methods mass spectrometry dissociation pattern endocyclic and exocyclic diterpene glycosides scale up UHPLC/Q-TOF-MS analysis glycerin process contaminants 3-monochloropropane-1,2-diol esters glycidyl esters glycyrrhizin SARS-CoV-2 surface plasmon resonance autodocking n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Special Issue in Honor of Professor James D. McChesney on the Occasion of his 80th Birthday |
| title | Special Issue in Honor of Professor James D. McChesney on the Occasion of his 80th Birthday |
| title_full | Special Issue in Honor of Professor James D. McChesney on the Occasion of his 80th Birthday |
| title_fullStr | Special Issue in Honor of Professor James D. McChesney on the Occasion of his 80th Birthday |
| title_full_unstemmed | Special Issue in Honor of Professor James D. McChesney on the Occasion of his 80th Birthday |
| title_short | Special Issue in Honor of Professor James D. McChesney on the Occasion of his 80th Birthday |
| title_sort | special issue in honor of professor james d mcchesney on the occasion of his 80th birthday |
| topic | Magnoliaceae GC-FID GC-MS mosquito control 1-decanol 1-octanol larvicidal activity deterrent biopesticides Persea americana Mill. avocado oil triglyceride fatty acid UHPLC/ESI-MS GC/MS quality evaluation Calu-3 cell line cancer chemotherapy drug resistance poly(ε-caprolactone) poly(ethylene glycol) isoflavonoids polyisoprenylated benzophenones propolis botanical sources oxyresveratrol Artocarpus lakoocha DNA damaging pro-oxidant medicinal plants cancer Ethiopia phytochemistry endophytic fungus Teratosphaeria teratopyrones naphtho-γ-pyrones nigerasperone A recombinant monoamine oxidase-A monoamine oxidase-B neurological disorder enzyme kinetics molecular docking inhibition activity flavonoid Atractylodes macrocephala wheat bran processing NMR atractylon derivatives isolation and identification Machaerium Rimachi 12161 machaerifurogerol 5-epi-machaerifurogerol machaeriol A–C machaeridiol A–C isoflavonoid MRSA VRE gram negative bacteria Torreya taxifolia plant pathogenic fungi Botryosphaeria dothidea malaria phytotoxin γ-lactam alkaloids Momordica charantia cucurbitane-type triterpene glycosides charantoside XV α-amylase α-glucosidase anti-inflammatory activity in silico study in vitro propagation medicinal crops phytomedicines Stevia rebaudiana HPTLC HPLC methods mass spectrometry dissociation pattern endocyclic and exocyclic diterpene glycosides scale up UHPLC/Q-TOF-MS analysis glycerin process contaminants 3-monochloropropane-1,2-diol esters glycidyl esters glycyrrhizin SARS-CoV-2 surface plasmon resonance autodocking n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | Magnoliaceae GC-FID GC-MS mosquito control 1-decanol 1-octanol larvicidal activity deterrent biopesticides Persea americana Mill. avocado oil triglyceride fatty acid UHPLC/ESI-MS GC/MS quality evaluation Calu-3 cell line cancer chemotherapy drug resistance poly(ε-caprolactone) poly(ethylene glycol) isoflavonoids polyisoprenylated benzophenones propolis botanical sources oxyresveratrol Artocarpus lakoocha DNA damaging pro-oxidant medicinal plants cancer Ethiopia phytochemistry endophytic fungus Teratosphaeria teratopyrones naphtho-γ-pyrones nigerasperone A recombinant monoamine oxidase-A monoamine oxidase-B neurological disorder enzyme kinetics molecular docking inhibition activity flavonoid Atractylodes macrocephala wheat bran processing NMR atractylon derivatives isolation and identification Machaerium Rimachi 12161 machaerifurogerol 5-epi-machaerifurogerol machaeriol A–C machaeridiol A–C isoflavonoid MRSA VRE gram negative bacteria Torreya taxifolia plant pathogenic fungi Botryosphaeria dothidea malaria phytotoxin γ-lactam alkaloids Momordica charantia cucurbitane-type triterpene glycosides charantoside XV α-amylase α-glucosidase anti-inflammatory activity in silico study in vitro propagation medicinal crops phytomedicines Stevia rebaudiana HPTLC HPLC methods mass spectrometry dissociation pattern endocyclic and exocyclic diterpene glycosides scale up UHPLC/Q-TOF-MS analysis glycerin process contaminants 3-monochloropropane-1,2-diol esters glycidyl esters glycyrrhizin SARS-CoV-2 surface plasmon resonance autodocking n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20220224_9783036527130_112 |