Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles

Dysregulation of Wnt signaling is known to be associated with various cancers. As such, identification of novel Wnt pathway targets in cancer and better characterization of already-known targets present exciting, emerging opportunities for cancer treatment. In this Special Issue, we feature papers w...

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Bibliografiske detaljer
Format:	Online
Sprog:	engelsk
Udgivet:	MDPI - Multidisciplinary Digital Publishing Institute 2022
Fag:	Wnt signaling synovial sarcoma TNIK NCB-0846 MYC hepatitis B virus HBV cancer liver cancer β-catenin TCF/LEF pancreatic cancer pancreatic stellate cells CBP p300 pancreatitis fibrosis just-right signaling APC colorectal cancer RNA-binding proteins Musashi drug discovery Notch signaling cancer therapy fungi secondary metabolite derivative microenvironment Wnt AML drug target signaling colorectal porcupine R-spondin serrated immunotherapy wnt vitamin D colon cancer L1 Wnt target genes cell adhesion NF-κB invasion and metastasis cancer stem cells EMT Lgr5 Wnt/beta-catenin signaling angiogenesis anti-angiogenic therapy gastrointestinal cancers therapeutic targeting of Wnt signaling β-catenin paradox molecular targeting urothelial cancer immune checkpoint inhibitor immunotherapy resistance IBD colitis β-catenin mutations tumor metabolism tumor immunology molecular therapeutics precision medicine astrocytic brain tumors DKKs GSK3β thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology
Online adgang:	ONIX_20220506_9783036535173_279
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Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles

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