Opioids and Their Receptors

Few neurotransmitter systems have fascinated as much as the opioid system (i.e., opioid ligands and their receptors). Over the years, scientific studies of the endogenous opioid system have uncovered a complex and subtle system that exhibits impressive diversity, based on its critical role in modula...

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Dettagli Bibliografici
Natura:	Online
Lingua:	inglese
Pubblicazione:	MDPI - Multidisciplinary Digital Publishing Institute 2022
Soggetti:	thiazole piperazine tail-clip hot-plate acetic acid-induced writhing test opioid prodynorphin epigenetics transcription human brain morphine dosing behavior locomotor activity tolerance µ-opioid receptor DAMGO SR-17018 buprenorphine nalbuphine kappa opioid receptor agonist pruritis scratching mice TAT-HIV cholestasis chloroquine deoxycholic acid analgesic δ opioid receptor G-protein-biased agonist opioid peptide rubiscolins µ-opioid analgesics angiotensin receptors chronic pain neuropathic pain delta opioid receptor inverse agonist irreversible antagonist non-competitive antagonist molecular pharmacology free fatty acid receptors lipids opioid receptor colitis chemotype high-throughput screen allosteric modulation beta-arrestin molecular dynamics opioid receptors β-amino acids peptide synthesis receptor binding studies functional assay nociceptin/orphanin FQ receptor NOP receptor ligands nociceptin N/OFQ analgesia GPCR HS-731 peripheral opioid agonist binding selectivity molecular docking molecular dynamics simulations n/a fluorescence cross-correlation spectroscopy (FCCS) G protein-coupled receptor (GPCR) serotonin thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry
Accesso online:	ONIX_20220621_9783036543529_104
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Opioids and Their Receptors

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