Anticancer Drugs 2021

The Special Issue "Anticancer Drugs 2021" of Pharmaceuticals is focused on recent significant advances in the design, synthesis, molecular mechanism of action and therapeutic applications of anticancer drugs. This collection of preclinical research papers and reviews includes designed chemotherapeut...

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Format:	Online
Sprache:	Englisch
Veröffentlicht:	MDPI - Multidisciplinary Digital Publishing Institute 2022
Schlagworte:	thymidylate synthase cytotoxicity 1,2,3-triazole 1,3,4-oxadiazole 5-fluoruracil pemetrexed docking 3,4′-bis-guanidino 3-amino-4′-guanidino diphenyl ether phenyl pyridyl ether intramolecular hydrogen bond cancer cell viability HL-60 BRAF apoptosis thieno[2,3-d][1,2,3]triazine acetamide H1299 HER2 EGFR Bcl-2 inhibitors Indole-based analogues benzimidazole MTT cytotoxic assay cell cycle analysis DNA fragmentation ELISA solid/lipid nanoparticles phenstatin letrozole tubulin polymerisation inhibitor aromatase inhibitor breast cancer hybrid molecule dual-targeting molecule designed multiple ligand NaMSA cyclophosphamide histopathology testis urinary bladder anticancer agents enantioselective synthesis gastric adenocarcinoma tryptophanol concentration-guided dosing model informed dosing physiologically based pharmacokinetics sorafenib tyrosil-DNA-phosphodiesterase 1 adamantane resin acid TDP1 cytotoxic agents apoptosis induction HT-29 cells MDA-MB-231 cells mechanism prediction STAT inhibitors miR-21 hydrazide derivatives nitrogen scaffolds mitoxantrone cardiotoxicity inflammation oxidative stress age cumulative dose Trk NTRK tissue-agnostic larotrectinib entrectinib Trk fusion protein kinase inhibitors USFDA cancer patent review generic product doxazosin MD simulations combretastatin A-4 cytotoxic activity hybrid compounds indazole mucin MUC1 MUC16 immunotherapy cancer vaccine CAR (chimeric antigen receptor) ADC (antibody-drug conjugate) thiourea interleukin-6 trypan blue assay chalcones exportin-1 covalent binding CovDock anticancer activity xanthone in vitro in vivo isolation synthesis heterocyclic compound benzenesulfonamides imidazoles alkylated colony formation tumor spheroids HDAC inhibitors chalcone dual inhibitors carvedilol kidney toxicity 7-deaza-4′-thioadenosine derivatives multi-kinase inhibitor anticancer nucleoside Imiquimod drug efflux multidrug resistance Toll-Like Receptor n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry
Online-Zugang:	ONIX_20220621_9783036543482_3
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Anticancer Drugs 2021

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