In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application
The Special Issue "In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application", edited by Marta Baiocchi and Ann Zeuner for Cancers, collects original research papers and reviews, depicting the current state and the perspectives of CRC models for preclinical and translational research...
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| Format: | Online |
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| Język: | angielski |
| Wydane: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Hasła przedmiotowe: | |
| Dostęp online: | ONIX_20220812_9783036539669_108 |
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| _version_ | 1869523984224092160 |
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| collection | Directory of Open Access Books |
| description | The Special Issue "In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application", edited by Marta Baiocchi and Ann Zeuner for Cancers, collects original research papers and reviews, depicting the current state and the perspectives of CRC models for preclinical and translational research. Original research papers published in this issue focus on some of the hottest topics in CRC research, such as circulating tumor cells, epigenetic regulation of stemness states, new therapeutic targets, molecular CRC classification and experimental CRC models such as organoids and PDXs. Additionally, four reviews on CRC stem cells, immunotherapy and drug discovery provide an updated viewpoint on key topics linking benchtop to bedside research in CRC. |
| format | Online |
| id | doab-20.500.12854ir-91229 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-912292024-03-28T03:31:15Z In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application Baiocchi, Marta Zeuner, Ann colorectal cancer organoids 3D bioprinting patient-derived xenograft cancer-on-chip drug combination cancer stem cells drug resistance clinical trials tumor-initiating cells tumor heterogeneity patient-derived cancer models single-cell RNA-sequencing tumor metabolism transcriptional programs tumor cell differentiation immunotherapy methods chromosomal instability DNA damage targeted therapy decitabine colon cancer DNA methylation clinical translation study machine learning patient-derived tumor organoid precision medicine radiation response rectal cancer PDX model CRC mutation analysis histological examination animal models in vitro culture cancer stem cell methods SATB2 colorectal carcinoma prognosis CDX2 circulating tumor cells CTC cluster size-based method ScreenCell® epithelial mesenchymal transition hypoxia HIF-1α immunofluorescence analysis sequential filtration thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) The Special Issue "In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application", edited by Marta Baiocchi and Ann Zeuner for Cancers, collects original research papers and reviews, depicting the current state and the perspectives of CRC models for preclinical and translational research. Original research papers published in this issue focus on some of the hottest topics in CRC research, such as circulating tumor cells, epigenetic regulation of stemness states, new therapeutic targets, molecular CRC classification and experimental CRC models such as organoids and PDXs. Additionally, four reviews on CRC stem cells, immunotherapy and drug discovery provide an updated viewpoint on key topics linking benchtop to bedside research in CRC. 2022-08-12T12:52:48Z 2022-08-12T12:52:48Z 2022 book ONIX_20220812_9783036539669_108 9783036539669 9783036539652 https://directory.doabooks.org/handle/20.500.12854/91229 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/5875 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-3965-2 10.3390/books978-3-0365-3965-2 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036539669 9783036539652 222 Basel open access |
| spellingShingle | colorectal cancer organoids 3D bioprinting patient-derived xenograft cancer-on-chip drug combination cancer stem cells drug resistance clinical trials tumor-initiating cells tumor heterogeneity patient-derived cancer models single-cell RNA-sequencing tumor metabolism transcriptional programs tumor cell differentiation immunotherapy methods chromosomal instability DNA damage targeted therapy decitabine colon cancer DNA methylation clinical translation study machine learning patient-derived tumor organoid precision medicine radiation response rectal cancer PDX model CRC mutation analysis histological examination animal models in vitro culture cancer stem cell methods SATB2 colorectal carcinoma prognosis CDX2 circulating tumor cells CTC cluster size-based method ScreenCell® epithelial mesenchymal transition hypoxia HIF-1α immunofluorescence analysis sequential filtration thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application |
| title | In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application |
| title_full | In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application |
| title_fullStr | In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application |
| title_full_unstemmed | In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application |
| title_short | In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application |
| title_sort | in vitro and in vivo models of colorectal cancer for clinical application |
| topic | colorectal cancer organoids 3D bioprinting patient-derived xenograft cancer-on-chip drug combination cancer stem cells drug resistance clinical trials tumor-initiating cells tumor heterogeneity patient-derived cancer models single-cell RNA-sequencing tumor metabolism transcriptional programs tumor cell differentiation immunotherapy methods chromosomal instability DNA damage targeted therapy decitabine colon cancer DNA methylation clinical translation study machine learning patient-derived tumor organoid precision medicine radiation response rectal cancer PDX model CRC mutation analysis histological examination animal models in vitro culture cancer stem cell methods SATB2 colorectal carcinoma prognosis CDX2 circulating tumor cells CTC cluster size-based method ScreenCell® epithelial mesenchymal transition hypoxia HIF-1α immunofluorescence analysis sequential filtration thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) |
| topic_facet | colorectal cancer organoids 3D bioprinting patient-derived xenograft cancer-on-chip drug combination cancer stem cells drug resistance clinical trials tumor-initiating cells tumor heterogeneity patient-derived cancer models single-cell RNA-sequencing tumor metabolism transcriptional programs tumor cell differentiation immunotherapy methods chromosomal instability DNA damage targeted therapy decitabine colon cancer DNA methylation clinical translation study machine learning patient-derived tumor organoid precision medicine radiation response rectal cancer PDX model CRC mutation analysis histological examination animal models in vitro culture cancer stem cell methods SATB2 colorectal carcinoma prognosis CDX2 circulating tumor cells CTC cluster size-based method ScreenCell® epithelial mesenchymal transition hypoxia HIF-1α immunofluorescence analysis sequential filtration thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) |
| url | ONIX_20220812_9783036539669_108 |