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Precision Medicine in Solid Tumors

In the era of precision medicine, the use of molecularly targeted therapies in selected patients has led to a paradigm change in cancer treatment. Multiple studies have demonstrated the benefits of therapies that are chosen based on the molecular profile of the tumor and also from the liquid biopsy....

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Format: Online
Language:English
Published: 2022
Subjects:
pediatric tumors
tumor mutational burden
TMB
whole-exome sequencing
gene panel sequencing
immune checkpoint inhibitors
glioblastoma prognosis
overall survival
extent of resection
random forest
Decision tree
personalized precision oncology
circulating free DNA
liquid biopsy
epidermal growth factor receptor
tyrosine kinase inhibitor
osimertinib
comprehensive genomic profiling
molecular genotyping
intratumor heterogeneity
multiple biopsies
tumor evolution
clonality classification
strategic therapeutic intervention
thymoma
driver mutation
sequencing
molecular barcoding
EGFR mutation
EGFR-TKI
cfDNA
NGS
digital enrichment
next-generation sequencing
solid cancer
universal health-care system
precision medicine
presumed germline findings
clinical guideline
non-small cell lung cancer
outcome
adjuvant chemotherapy
anaplastic lymphoma receptor tyrosine kinase
HNSCC
ctDNA
tDNA
DDR genes
PARP inhibitors
new drug development
next-generation sequencing (NGS)
open data
regulatory reform
tumor profiling test
triple-negative breast cancer (TNBC)
breast cancer
targeted therapy
TNBC subtypes
immunotherapy
cancer
screening
smoking
electronic records
PD-L1
cancer-associated fibroblasts
resistance
chemotherapy
CTC
immunocytochemistry
parallel double-detection
laboratory-friendly
n/a
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
Online Access:ONIX_20220916_9783036547916_6
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