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Brain-Targeted Drug Delivery

Brain diseases currently affect one in six people worldwide; they include a wide range of neurological diseases, from Alzheimer’s and Parkinson’s diseases to epilepsy, brain injuries, brain cancer, neuroinfections, and strokes. The treatment of these diseases is complex and limited due to the presen...

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Format: Online
Jezik:angleščina
Izdano: MDPI - Multidisciplinary Digital Publishing Institute 2022
Teme:
drug delivery into the brain
transendothelium based on receptor-mediated transcytosis
immunotherapy
Alzheimer’s disease
anti-tau and anti-receptor bispecific monoclonal antibodies
Alzheimer’s disease-relevant tau species
temporal-spatial pathological Aβ and tau distribution
interactions between Aβ and tau
tau clearance in microglia
tau clearance in neurons
liposome
nanoparticle
seizure
laser
ultrasound
naringenin
nanostructured lipid carrier
intranasal delivery
central composite rotatable design
depression
pomegranate seed oil
nasal delivery system
memory impairment
movement impairment
delivery to brain
improved memory
phospholipid oily gel
high-grade glioma
diffuse midline glioma
glioblastoma
IL-13Rα2
IL-13
immunotoxin
targeted therapy
GB-13
IL13.E13K-PE4E
receptor expression
acetaminophen
blood–brain barrier
claudin-5
CNS drug delivery
opioids
tight junction
microdialysis
cerebral open flow microperfusion
electrochemical biosensors
macromolecules
tolcapone
microparticles
nanoparticles
PLGA
Parkinson’s disease
nose to brain delivery
gene therapy
polyplexes
hyaluronidase
glycol chitosan
brain cancer
chemoattractant
CXCL
CXCR
glioblastoma multiforme
3D cell culture systems
non-human primate
convection-enhanced delivery
neurosurgery
optogenetics
blood-brain barrier
brain targeted therapy
drug delivery
cerebrospinal fluid microcirculation
brain biodistribution
n/a
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
Online dostop:ONIX_20221025_9783036552828_48
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