Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression

The aim of this Special Issue is to collect reports regarding all the recent strategies, directed at the improvement of antineoplastic activity of drugs in cancer progression, engaging all the expertise needed for the development of new anticancer drugs: medicinal chemistry, pharmacology, molecular...

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Format: Online
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2023
Subjects:
SAR
CTC
Online Access:ONIX_20230105_9783036559285_30
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collection Directory of Open Access Books
description The aim of this Special Issue is to collect reports regarding all the recent strategies, directed at the improvement of antineoplastic activity of drugs in cancer progression, engaging all the expertise needed for the development of new anticancer drugs: medicinal chemistry, pharmacology, molecular biology, and computational and drug delivery studies.
format Online
id doab-20.500.12854ir-95801
institution Directory of Open Access Books
language eng
publishDate 2023
publishDateRange 2023
publishDateSort 2023
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-958012024-03-28T03:33:53Z Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression Stefanachi, Angela EGR-1 flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences The aim of this Special Issue is to collect reports regarding all the recent strategies, directed at the improvement of antineoplastic activity of drugs in cancer progression, engaging all the expertise needed for the development of new anticancer drugs: medicinal chemistry, pharmacology, molecular biology, and computational and drug delivery studies. 2023-01-05T12:33:29Z 2023-01-05T12:33:29Z 2022 book ONIX_20230105_9783036559285_30 9783036559285 9783036559278 https://directory.doabooks.org/handle/20.500.12854/95801 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/6457 https://mdpi.com/books/pdfview/book/6457 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-5927-8 10.3390/books978-3-0365-5927-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036559285 9783036559278 416 Basel open access
spellingShingle EGR-1
flavonoid
(E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile
MDA-MB-231
MMP9
TNFα
pancreatic ductal adenocarcinoma
cyclodextrin inclusion complex
phase solubility studies
preformulation studies
biphenylnicotinamide derivatives
dual inhibitor
EGFR
VEGFR2
ligand-based pharmacophore
molecular docking
molecular dynamics
leukemias
doxorubicin
inflammation
drug delivery
tumor targeting
elastin-like polypeptide
cell penetrating peptide
matrix metalloproteinase
doxorubicin resistance
photosensitizer delivery system
PAMAM dendrimer
photodynamic therapy
cytotoxicity
phototoxicity
colorectal adenocarcinoma
dicarboximides
chemical synthesis
apoptosis
kinases
anticancer
gene profiling
SAR
biomarkers
colorectal cancer
early detection examination
liquid biopsy
personalized medicine
tumor treatment
exosomes
ctDNA
CTC
cytotoxic activity
pyrazole derivatives
MTT assay
ADMET analysis
single-crystal diffraction
FTIR spectroscopy
NMR spectroscopy thermogravimetric analysis
acute myelogenous leukemia
platelets
microparticles
γδ T cells
immunotherapy
tumor resistance
combination therapy
tumor microenvironment
immune checkpoint inhibitor
neuroblastoma
molecular iodine
cyclophosphamide
xenografts
metronomic therapy
tamoxifen
CYP2D6
MCF-7
Ishikawa cells
SERM
TNBC
uterotrophic
α-mangostin
poly(amidoamine) dendrimer
targeted drug delivery
biotin targeting
glioblastoma multiforme
squamous cell carcinoma
antiparasitic therapy
diclofenac
indomethacin
oleanolic acid derivative conjugates
NF-κB
Nrf2
MAPKs
PSN-1 cells
reactive oxygen species
glioblastoma
brain tumor
extracellular vesicles
pancreatic cancer
paclitaxel
clathrin
endocytosis
sulforaphane
nicotine
metalloproteinase-9
gastric cancer
cell invasion
Arylquin 1
colon cancer
tumor progression
azelastine
oxidative stress
autophagy
mitotic catastrophe
chronic myeloid leukemia
imatinib
tyrosine kinase
ketoconazole
P-glycoprotein
drug efflux transporter
non-small-cell lung cancer
cisplatin resistance
aldehyde dehydrogenase
isothiocyanates
disulfiram
epithelial to mesenchymal transition
aminopeptidase N
acetamidophenones
Schiff bases
semicarbazones
thiosemicarbazones
inhibition of proliferation
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
title Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
title_full Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
title_fullStr Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
title_full_unstemmed Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
title_short Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
title_sort strategies to improve antineoplastic activity of drugs in cancer progression
topic EGR-1
flavonoid
(E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile
MDA-MB-231
MMP9
TNFα
pancreatic ductal adenocarcinoma
cyclodextrin inclusion complex
phase solubility studies
preformulation studies
biphenylnicotinamide derivatives
dual inhibitor
EGFR
VEGFR2
ligand-based pharmacophore
molecular docking
molecular dynamics
leukemias
doxorubicin
inflammation
drug delivery
tumor targeting
elastin-like polypeptide
cell penetrating peptide
matrix metalloproteinase
doxorubicin resistance
photosensitizer delivery system
PAMAM dendrimer
photodynamic therapy
cytotoxicity
phototoxicity
colorectal adenocarcinoma
dicarboximides
chemical synthesis
apoptosis
kinases
anticancer
gene profiling
SAR
biomarkers
colorectal cancer
early detection examination
liquid biopsy
personalized medicine
tumor treatment
exosomes
ctDNA
CTC
cytotoxic activity
pyrazole derivatives
MTT assay
ADMET analysis
single-crystal diffraction
FTIR spectroscopy
NMR spectroscopy thermogravimetric analysis
acute myelogenous leukemia
platelets
microparticles
γδ T cells
immunotherapy
tumor resistance
combination therapy
tumor microenvironment
immune checkpoint inhibitor
neuroblastoma
molecular iodine
cyclophosphamide
xenografts
metronomic therapy
tamoxifen
CYP2D6
MCF-7
Ishikawa cells
SERM
TNBC
uterotrophic
α-mangostin
poly(amidoamine) dendrimer
targeted drug delivery
biotin targeting
glioblastoma multiforme
squamous cell carcinoma
antiparasitic therapy
diclofenac
indomethacin
oleanolic acid derivative conjugates
NF-κB
Nrf2
MAPKs
PSN-1 cells
reactive oxygen species
glioblastoma
brain tumor
extracellular vesicles
pancreatic cancer
paclitaxel
clathrin
endocytosis
sulforaphane
nicotine
metalloproteinase-9
gastric cancer
cell invasion
Arylquin 1
colon cancer
tumor progression
azelastine
oxidative stress
autophagy
mitotic catastrophe
chronic myeloid leukemia
imatinib
tyrosine kinase
ketoconazole
P-glycoprotein
drug efflux transporter
non-small-cell lung cancer
cisplatin resistance
aldehyde dehydrogenase
isothiocyanates
disulfiram
epithelial to mesenchymal transition
aminopeptidase N
acetamidophenones
Schiff bases
semicarbazones
thiosemicarbazones
inhibition of proliferation
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet EGR-1
flavonoid
(E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile
MDA-MB-231
MMP9
TNFα
pancreatic ductal adenocarcinoma
cyclodextrin inclusion complex
phase solubility studies
preformulation studies
biphenylnicotinamide derivatives
dual inhibitor
EGFR
VEGFR2
ligand-based pharmacophore
molecular docking
molecular dynamics
leukemias
doxorubicin
inflammation
drug delivery
tumor targeting
elastin-like polypeptide
cell penetrating peptide
matrix metalloproteinase
doxorubicin resistance
photosensitizer delivery system
PAMAM dendrimer
photodynamic therapy
cytotoxicity
phototoxicity
colorectal adenocarcinoma
dicarboximides
chemical synthesis
apoptosis
kinases
anticancer
gene profiling
SAR
biomarkers
colorectal cancer
early detection examination
liquid biopsy
personalized medicine
tumor treatment
exosomes
ctDNA
CTC
cytotoxic activity
pyrazole derivatives
MTT assay
ADMET analysis
single-crystal diffraction
FTIR spectroscopy
NMR spectroscopy thermogravimetric analysis
acute myelogenous leukemia
platelets
microparticles
γδ T cells
immunotherapy
tumor resistance
combination therapy
tumor microenvironment
immune checkpoint inhibitor
neuroblastoma
molecular iodine
cyclophosphamide
xenografts
metronomic therapy
tamoxifen
CYP2D6
MCF-7
Ishikawa cells
SERM
TNBC
uterotrophic
α-mangostin
poly(amidoamine) dendrimer
targeted drug delivery
biotin targeting
glioblastoma multiforme
squamous cell carcinoma
antiparasitic therapy
diclofenac
indomethacin
oleanolic acid derivative conjugates
NF-κB
Nrf2
MAPKs
PSN-1 cells
reactive oxygen species
glioblastoma
brain tumor
extracellular vesicles
pancreatic cancer
paclitaxel
clathrin
endocytosis
sulforaphane
nicotine
metalloproteinase-9
gastric cancer
cell invasion
Arylquin 1
colon cancer
tumor progression
azelastine
oxidative stress
autophagy
mitotic catastrophe
chronic myeloid leukemia
imatinib
tyrosine kinase
ketoconazole
P-glycoprotein
drug efflux transporter
non-small-cell lung cancer
cisplatin resistance
aldehyde dehydrogenase
isothiocyanates
disulfiram
epithelial to mesenchymal transition
aminopeptidase N
acetamidophenones
Schiff bases
semicarbazones
thiosemicarbazones
inhibition of proliferation
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20230105_9783036559285_30