Molecular Mechanisms and Therapies of Colorectal Cancer

Colorectal cancer (CRC) is currently the third leading cause of cancer-related mortality, with 1.9 million incidence cases and 0.9 million deaths worldwide. The global number of new CRC cases is predicted to reach 3.2 million in 2040, based on the projection of aging, population growth, and human de...

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Detalhes bibliográficos
Formato:	Online
Idioma:	inglês
Publicado em:	MDPI - Multidisciplinary Digital Publishing Institute 2023
Assuntos:	colorectal cancer miRNA ceRNA lncRNA circRNA sponging noninvasive biomarkers MiR-199b tumor suppressor prognosis LARC HOX HOXB9 colorectal liver metastases metastatic colorectal cancer structural variants common fragile sites platinum therapy stalled replication fork surgical oncology liver regeneration immunology hepatic tissue-resident memory T cells liver neoplasms neoplasm metastasis proteomics biomarkers mass spectrometry microRNA hypoxia hypoxia-regulated microRNAs fatty acid synthase lipid metabolism colorectal cancer initiation Apc mutation epigenetics methylation biomarker S-Adenosylmethionine breast cancer Notch metastasis EMT targeted sequencing inflammatory bowel diseases colitis-associated cancer phosphatidylinositol 3-kinase sortilin neurotensin neurotensin receptor-3 soluble sortilin cell signaling cell morphology colorectal carcinoma early onset CRC multi-omics lymphovascular invasion perineural invasion DNA damage repair DNA replication repair MMR base excision repair FASN CTLA4 HAVCR2 TGF-β signaling targeting therapy immune-suppressive barrier properties colon heterogeneity cytokines tumor necrosis factor alpha interleukin 10 tight junction proteins 1,2-dimethylhydrazine rat epithelial-to-mesenchymal transition tumor-associated macrophages thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
Acesso em linha:	ONIX_20230202_9783036565477_136
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Molecular Mechanisms and Therapies of Colorectal Cancer

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