Pathogenesis and Targeted Therapy of Epilepsy

Epilepsy is one of the most prevalent neurological disorders and is characterized by recurrent seizures resulting from abnormal neuronal excitability in the central nervous system. Despite the availability of thirty-six antiseizure medications, about one-third of patients with epilepsy do not respon...

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Bibliografiska uppgifter
Materialtyp:	Online
Språk:	engelska
Utgiven:	MDPI - Multidisciplinary Digital Publishing Institute 2023
Ämnen:	3CAI GRIA1 GRIA2 intractable epilepsy PICK1 protein kinase C pericytes mural cells cytokine blood-brain barrier neuroinflammation 3-phosphoinositide-dependent protein kinase-1 AKT cyclosporin A GluA1 GluR1 PDK1 refractory seizure temporal lobe epilepsy hippocampus 4-aminopyridine epilepsy model long-term potentiation AMPA receptor audiogenic epilepsy rodents fear reaction behavior genetics c-Fos early gene activation epileptogenesis lipopolysaccharide pentylenetetrazole post-traumatic epilepsy seizure susceptibility traumatic brain injury epilepsy ghrelin ghrelin receptor anxiety TRPV1 channels neuronal activity neuropsychiatric comorbidity immunofluorescence audiogenic kindling acoustically evoked seizures EACT generalized tonic-clonic seizures inherited epilepsy TMEM1A channels wild running seizures astrocyte ML365 pharmacoresistant epilepsy cortical atrophy hippocampal atrophy intracerebral electrode magnetic resonance imaging posttraumatic epilepsy n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PH Physics
Länkar:	ONIX_20230307_9783036564364_22
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Pathogenesis and Targeted Therapy of Epilepsy

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