Amyloid-β

This reprint includes 16 original articles published in a Special Issue that focuses on the pathological significance of amyloid-β in neurodegenerative diseases, such as Alzheimer’s disease, the main cause of dementia. Collections in this reprint provide novel insights into the underlying mechanisms...

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collection Directory of Open Access Books
description This reprint includes 16 original articles published in a Special Issue that focuses on the pathological significance of amyloid-β in neurodegenerative diseases, such as Alzheimer’s disease, the main cause of dementia. Collections in this reprint provide novel insights into the underlying mechanisms and therapeutic potentials of repositioning drugs and new agents for Alzheimer’s disease and related dementias. These findings are expected to contribute to the development of innovative strategies for the prevention and treatment of such diseases.
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institution Directory of Open Access Books
language eng
publishDate 2023
publishDateRange 2023
publishDateSort 2023
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-981072024-03-31T13:09:02Z Amyloid-β Tanaka, Masashi Ono, Kenjiro Saito, Satoshi activation phenotypes microglia neuroinflammation immunohistochemistry temporal cortex Alzheimer’s disease amyloid amyloid β-protein (Aβ) mAb158 oligomers protofibrils amyloid aggregation supported lipid bilayers time-lapse AFM molecular dynamics simulation alzheimer’s disease amyloid β bryostatin-1 ECE1 iPS nELAV neurotoxicity oligomer protein kinase C α-secretase APP mutation recessive inheritance familial Alzheimer’s disease Aβ oligomers amyloid imaging microbiota bacterial amyloid FUBA curli CsgA amyloid beta oxidative stress supplement phosphodiesterase III inhibitor cerebral micro-hemorrhage(s) cerebral amyloid angiopathy amyloid-β protein transgenic mice NMR CD Aβ β-amyloid peptide α/β-discordant Dutch-type mutation E22Q FAD Amyloid β Polyphenol Pro-oxidant Alzheimer’s Disease molecular imaging amyloid β-peptides islet amyloid polypeptide high-speed atomic force microscopy amyloid PET tau PET amyloid precursor protein mutation cerebellum PBB3 PiB axon traditional medicines Polygalae Radix diosgenin naringenin kihito amyloid-β antimicrobial antiviral antimicrobial peptide neurodegenerative disease misfolding fluorescence microscopy FRET n/a thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine This reprint includes 16 original articles published in a Special Issue that focuses on the pathological significance of amyloid-β in neurodegenerative diseases, such as Alzheimer’s disease, the main cause of dementia. Collections in this reprint provide novel insights into the underlying mechanisms and therapeutic potentials of repositioning drugs and new agents for Alzheimer’s disease and related dementias. These findings are expected to contribute to the development of innovative strategies for the prevention and treatment of such diseases. 2023-03-07T16:34:23Z 2023-03-07T16:34:23Z 2023 book ONIX_20230307_9783036567129_117 9783036567129 9783036567136 https://directory.doabooks.org/handle/20.500.12854/98107 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/6880 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-6713-6 10.3390/books978-3-0365-6713-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036567129 9783036567136 276 Basel open access
spellingShingle activation phenotypes
microglia
neuroinflammation
immunohistochemistry
temporal cortex
Alzheimer’s disease
amyloid
amyloid β-protein (Aβ)
mAb158
oligomers
protofibrils
amyloid aggregation
supported lipid bilayers
time-lapse AFM
molecular dynamics simulation
alzheimer’s disease
amyloid β
bryostatin-1
ECE1
iPS
nELAV
neurotoxicity
oligomer
protein kinase C
α-secretase
APP mutation
recessive inheritance
familial Alzheimer’s disease
Aβ oligomers
amyloid imaging
microbiota
bacterial amyloid
FUBA
curli
CsgA
amyloid beta
oxidative stress
supplement
phosphodiesterase III inhibitor
cerebral micro-hemorrhage(s)
cerebral amyloid angiopathy
amyloid-β protein
transgenic mice
NMR
CD

β-amyloid peptide
α/β-discordant
Dutch-type mutation
E22Q
FAD
Amyloid β
Polyphenol
Pro-oxidant
Alzheimer’s Disease
molecular imaging
amyloid β-peptides
islet amyloid polypeptide
high-speed atomic force microscopy
amyloid PET
tau PET
amyloid precursor protein
mutation
cerebellum
PBB3
PiB
axon
traditional medicines
Polygalae Radix
diosgenin
naringenin
kihito
amyloid-β
antimicrobial
antiviral
antimicrobial peptide
neurodegenerative disease
misfolding
fluorescence microscopy
FRET
n/a
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine
Amyloid-β
title Amyloid-β
title_full Amyloid-β
title_fullStr Amyloid-β
title_full_unstemmed Amyloid-β
title_short Amyloid-β
title_sort amyloid β
topic activation phenotypes
microglia
neuroinflammation
immunohistochemistry
temporal cortex
Alzheimer’s disease
amyloid
amyloid β-protein (Aβ)
mAb158
oligomers
protofibrils
amyloid aggregation
supported lipid bilayers
time-lapse AFM
molecular dynamics simulation
alzheimer’s disease
amyloid β
bryostatin-1
ECE1
iPS
nELAV
neurotoxicity
oligomer
protein kinase C
α-secretase
APP mutation
recessive inheritance
familial Alzheimer’s disease
Aβ oligomers
amyloid imaging
microbiota
bacterial amyloid
FUBA
curli
CsgA
amyloid beta
oxidative stress
supplement
phosphodiesterase III inhibitor
cerebral micro-hemorrhage(s)
cerebral amyloid angiopathy
amyloid-β protein
transgenic mice
NMR
CD

β-amyloid peptide
α/β-discordant
Dutch-type mutation
E22Q
FAD
Amyloid β
Polyphenol
Pro-oxidant
Alzheimer’s Disease
molecular imaging
amyloid β-peptides
islet amyloid polypeptide
high-speed atomic force microscopy
amyloid PET
tau PET
amyloid precursor protein
mutation
cerebellum
PBB3
PiB
axon
traditional medicines
Polygalae Radix
diosgenin
naringenin
kihito
amyloid-β
antimicrobial
antiviral
antimicrobial peptide
neurodegenerative disease
misfolding
fluorescence microscopy
FRET
n/a
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine
topic_facet activation phenotypes
microglia
neuroinflammation
immunohistochemistry
temporal cortex
Alzheimer’s disease
amyloid
amyloid β-protein (Aβ)
mAb158
oligomers
protofibrils
amyloid aggregation
supported lipid bilayers
time-lapse AFM
molecular dynamics simulation
alzheimer’s disease
amyloid β
bryostatin-1
ECE1
iPS
nELAV
neurotoxicity
oligomer
protein kinase C
α-secretase
APP mutation
recessive inheritance
familial Alzheimer’s disease
Aβ oligomers
amyloid imaging
microbiota
bacterial amyloid
FUBA
curli
CsgA
amyloid beta
oxidative stress
supplement
phosphodiesterase III inhibitor
cerebral micro-hemorrhage(s)
cerebral amyloid angiopathy
amyloid-β protein
transgenic mice
NMR
CD

β-amyloid peptide
α/β-discordant
Dutch-type mutation
E22Q
FAD
Amyloid β
Polyphenol
Pro-oxidant
Alzheimer’s Disease
molecular imaging
amyloid β-peptides
islet amyloid polypeptide
high-speed atomic force microscopy
amyloid PET
tau PET
amyloid precursor protein
mutation
cerebellum
PBB3
PiB
axon
traditional medicines
Polygalae Radix
diosgenin
naringenin
kihito
amyloid-β
antimicrobial
antiviral
antimicrobial peptide
neurodegenerative disease
misfolding
fluorescence microscopy
FRET
n/a
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine
url ONIX_20230307_9783036567129_117