Novel Therapeutic Considerations in Bone and Soft Tissue Sarcoma

Sarcomas are a group of rare cancers that arise in connective tissues of the body. Surgical resection is pivotal for the management of locoregional disease. In locally advanced or metastatic disease settings, systemic therapy has an important role in the multidisciplinary management of sarcoma. Cyto...

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Detalles Bibliográficos
Formato:	Online
Idioma:	inglés
Publicado:	MDPI - Multidisciplinary Digital Publishing Institute 2023
Subjects:	osteosarcoma survival prognosis age groups chemotherapy metastasis local recurrence TEM1 VEGFR-1 EGFR VEGFR-2 IGF-1R PDGFRα CD40 image guided surgery near-infra red fluorescence soft tissue sarcomas angiosarcoma paclitaxel pazopanib efficacy toxicity progression-free survival sarcoma radiotherapy neoadjuvant therapy hypofractionated radiotherapy thermotherapy hyperthermia incisional biopsy core needle biopsy sensitivity bone soft tissue LC3B ATG16L1 p62 M6PR PD-L1 CD8 notochord tumor endoprosthesis megaprosthesis periprosthetic joint infection revision surgery bone sarcoma extracellular acidosis tumour microenvironment tumour-associated stroma acid-sensing ion channels vacuolar-ATP-ase carbonic anhydrase IX acridine orange soft tissue sarcoma immune monitoring immunophenotyping cytokines immune checkpoints gene expression Angiosarcoma biomarkers tumor microenvironment immunotherapy next-generation sequencing whole transcriptome sequencing thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
Acceso en liña:	ONIX_20230405_9783036570150_205
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Novel Therapeutic Considerations in Bone and Soft Tissue Sarcoma

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