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Neurodegenerative Diseases

Neurodegenerative diseases (NDs) are a heterogeneous group of complex diseases characterized by neuronal loss and progressive degeneration of different areas of the nervous system. NDs represent a significant health problem worldwide, with an increasing incidence rate. Although the exact pathogenesi...

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Gardado en:
Formato: Online
Idioma:inglés
Publicado: MDPI - Multidisciplinary Digital Publishing Institute 2023
Subjects:
menopause
estrogen
neurodegenerative disease
Alzheimer’s disease
IGF-1
NMDAR
Parkinson’s disease
neurodegeneration
genetics
non-coding RNAs
microbiome
mitochondria
epigenetics
biomarkers
precision medicine
EAE
glutamate receptor antagonist
excitotoxicity
oxidative stress
-SH groups
superoxide dismutase
circulating microRNA
relapsing–remitting multiple sclerosis
secondary progressive multiple sclerosis
biomarker
neuroinflammation
Rab1
GTPases
secretory pathway
Golgi fragmentation
autophagy
α-synuclein
LRRK2
mercury
central nervous system
proteomic
motor functions
rotenone
dopamine
dopamine-D3-receptor
buspirone
chicoric acid
peripheral immune system
spleen
gut
6-hydroxydopamine
apoptosis
mitochondrial membrane potential
neurodegenerative diseases
cell culture techniques
neurodegenerative disorders
neuroprotective effect
biological products
striatum
caspase-3
spiny projection neurons
dendritic spines
long-term depression
Q-VD-OPh
mice
blood–brain barrier
extracellular matrix
fibronectin
liposomes
multiple sclerosis
nanomedicine
oligodendrocytes
PLGA
remyelination
therapeutic targets
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
Acceso en liña:ONIX_20230405_9783036570754_235
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Summary:Neurodegenerative diseases (NDs) are a heterogeneous group of complex diseases characterized by neuronal loss and progressive degeneration of different areas of the nervous system. NDs represent a significant health problem worldwide, with an increasing incidence rate. Although the exact pathogenesis of NDs remains unclear, a complex interaction among genetic, epigenetic, and environmental factors has been proposed. To date, no effective therapeutics have been developed to slow, halt, or prevent any NDs. Thus, information on the molecular mechanisms underlying the pathogenesis of NDs is strongly sought after. This Special Issue collected papers discussing advances in the field of NDs.

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