Application of LC-MS/MS in the Mycotoxins Studies
Mycotoxins are secondary metabolites produced by the fungi of different species (mainly Aspergillus, Fusarium, and Penicillium), with toxic effects for humans and animals. These mycotoxins can contaminate food and feed. The European Union (EU) has established the maximum permitted or recommended lev...
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| Språk: | engelska |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Länkar: | ONIX_20210501_9783039362066_366 |
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| description | Mycotoxins are secondary metabolites produced by the fungi of different species (mainly Aspergillus, Fusarium, and Penicillium), with toxic effects for humans and animals. These mycotoxins can contaminate food and feed. The European Union (EU) has established the maximum permitted or recommended levels for well-known mycotoxins in different foodstuffs. However, there are other mycotoxins that are not included in the regulations: the “emerging mycotoxins” (whose toxicity is still not clear), and the “modified or masked mycotoxins” (produced as a consequence of a detoxification strategy of the host plant of the fungus or during food processing). These mycotoxins could pose a risk and should also be taken into account. In order to assure consumers’ health, analytical methods for the accurate determination of mycotoxins in different food matrices and feeds are required. In this sense, liquid chromatography tandem mass spectrometry (LC–MS/MS) is a powerful tool for their unique identification and quantification. Moreover, the use of high-resolution mass spectrometry (HRMS) allows one to identify novel mycotoxins and targeted/untargeted approaches for study. This Special Issue compiles recent applications of LC–MS/MS in mycotoxin studies, as well as the development and validation of new analytical methods for their identification and quantification in different food matrices and feed, occurrence studies, and the biomonitoring of mycotoxins and their metabolites in biological fluids. |
| format | Online |
| id | doab-20.500.12854ir-68620 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-686202024-03-31T13:10:02Z Application of LC-MS/MS in the Mycotoxins Studies Gámiz-Gracia, Laura García-Campaña, Ana M. Arroyo-Manzanares, Natalia cereals mycotoxigenic fungi phylogeny deoxynivalenol zearalenone Sub-Saharan Africa aflatoxins mycotoxins total diet study food contaminants LC-MS/MS Alternaria toxins grape modified QuEChERS UHPLC-MS/MS n/a traditional sorghum malts Aspergillus LC/MS/MS Biomarkers exposure LC-HRMS pig broiler chicken multi-mycotoxin stability malting brewing beer feed liquid chromatography fluorescence detection mass spectrometry solid-liquid extraction co-occurrence metabolism high-resolution mass spectrometry (HRMS) microsomal incubation glucuronidation human biomonitoring UPLC-MS/MS rumen fluid maize silage matrix-matched moniliformin lanthanide complexes LC-UV collaborative study isotopic dilution compliance infant food emergent mycotoxins urine dispersive solid-phase extraction magnetic carbon nanotube composite pesticides Q-Exactive Orbitrap CBD capsule nutraceutical Fusarium maize masked mycotoxins agricultural regions South Africa Mycotoxins exposure assessment Algeria mixed feed rations QuEChERS dispersive solid phase extraction high-resolution mass spectrometry data independent SWATH thema EDItEUR::M Medicine and Nursing Mycotoxins are secondary metabolites produced by the fungi of different species (mainly Aspergillus, Fusarium, and Penicillium), with toxic effects for humans and animals. These mycotoxins can contaminate food and feed. The European Union (EU) has established the maximum permitted or recommended levels for well-known mycotoxins in different foodstuffs. However, there are other mycotoxins that are not included in the regulations: the “emerging mycotoxins” (whose toxicity is still not clear), and the “modified or masked mycotoxins” (produced as a consequence of a detoxification strategy of the host plant of the fungus or during food processing). These mycotoxins could pose a risk and should also be taken into account. In order to assure consumers’ health, analytical methods for the accurate determination of mycotoxins in different food matrices and feeds are required. In this sense, liquid chromatography tandem mass spectrometry (LC–MS/MS) is a powerful tool for their unique identification and quantification. Moreover, the use of high-resolution mass spectrometry (HRMS) allows one to identify novel mycotoxins and targeted/untargeted approaches for study. This Special Issue compiles recent applications of LC–MS/MS in mycotoxin studies, as well as the development and validation of new analytical methods for their identification and quantification in different food matrices and feed, occurrence studies, and the biomonitoring of mycotoxins and their metabolites in biological fluids. 2021-05-01T15:15:59Z 2021-05-01T15:15:59Z 2020 book ONIX_20210501_9783039362066_366 9783039362066 9783039362073 https://directory.doabooks.org/handle/20.500.12854/68620 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2382 https://mdpi.com/books/pdfview/book/2382 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03936-207-3 10.3390/books978-3-03936-207-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039362066 9783039362073 302 Basel, Switzerland open access |
| spellingShingle | cereals mycotoxigenic fungi phylogeny deoxynivalenol zearalenone Sub-Saharan Africa aflatoxins mycotoxins total diet study food contaminants LC-MS/MS Alternaria toxins grape modified QuEChERS UHPLC-MS/MS n/a traditional sorghum malts Aspergillus LC/MS/MS Biomarkers exposure LC-HRMS pig broiler chicken multi-mycotoxin stability malting brewing beer feed liquid chromatography fluorescence detection mass spectrometry solid-liquid extraction co-occurrence metabolism high-resolution mass spectrometry (HRMS) microsomal incubation glucuronidation human biomonitoring UPLC-MS/MS rumen fluid maize silage matrix-matched moniliformin lanthanide complexes LC-UV collaborative study isotopic dilution compliance infant food emergent mycotoxins urine dispersive solid-phase extraction magnetic carbon nanotube composite pesticides Q-Exactive Orbitrap CBD capsule nutraceutical Fusarium maize masked mycotoxins agricultural regions South Africa Mycotoxins exposure assessment Algeria mixed feed rations QuEChERS dispersive solid phase extraction high-resolution mass spectrometry data independent SWATH thema EDItEUR::M Medicine and Nursing Application of LC-MS/MS in the Mycotoxins Studies |
| title | Application of LC-MS/MS in the Mycotoxins Studies |
| title_full | Application of LC-MS/MS in the Mycotoxins Studies |
| title_fullStr | Application of LC-MS/MS in the Mycotoxins Studies |
| title_full_unstemmed | Application of LC-MS/MS in the Mycotoxins Studies |
| title_short | Application of LC-MS/MS in the Mycotoxins Studies |
| title_sort | application of lc ms ms in the mycotoxins studies |
| topic | cereals mycotoxigenic fungi phylogeny deoxynivalenol zearalenone Sub-Saharan Africa aflatoxins mycotoxins total diet study food contaminants LC-MS/MS Alternaria toxins grape modified QuEChERS UHPLC-MS/MS n/a traditional sorghum malts Aspergillus LC/MS/MS Biomarkers exposure LC-HRMS pig broiler chicken multi-mycotoxin stability malting brewing beer feed liquid chromatography fluorescence detection mass spectrometry solid-liquid extraction co-occurrence metabolism high-resolution mass spectrometry (HRMS) microsomal incubation glucuronidation human biomonitoring UPLC-MS/MS rumen fluid maize silage matrix-matched moniliformin lanthanide complexes LC-UV collaborative study isotopic dilution compliance infant food emergent mycotoxins urine dispersive solid-phase extraction magnetic carbon nanotube composite pesticides Q-Exactive Orbitrap CBD capsule nutraceutical Fusarium maize masked mycotoxins agricultural regions South Africa Mycotoxins exposure assessment Algeria mixed feed rations QuEChERS dispersive solid phase extraction high-resolution mass spectrometry data independent SWATH thema EDItEUR::M Medicine and Nursing |
| topic_facet | cereals mycotoxigenic fungi phylogeny deoxynivalenol zearalenone Sub-Saharan Africa aflatoxins mycotoxins total diet study food contaminants LC-MS/MS Alternaria toxins grape modified QuEChERS UHPLC-MS/MS n/a traditional sorghum malts Aspergillus LC/MS/MS Biomarkers exposure LC-HRMS pig broiler chicken multi-mycotoxin stability malting brewing beer feed liquid chromatography fluorescence detection mass spectrometry solid-liquid extraction co-occurrence metabolism high-resolution mass spectrometry (HRMS) microsomal incubation glucuronidation human biomonitoring UPLC-MS/MS rumen fluid maize silage matrix-matched moniliformin lanthanide complexes LC-UV collaborative study isotopic dilution compliance infant food emergent mycotoxins urine dispersive solid-phase extraction magnetic carbon nanotube composite pesticides Q-Exactive Orbitrap CBD capsule nutraceutical Fusarium maize masked mycotoxins agricultural regions South Africa Mycotoxins exposure assessment Algeria mixed feed rations QuEChERS dispersive solid phase extraction high-resolution mass spectrometry data independent SWATH thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20210501_9783039362066_366 |