Advances in Celiac Disease

The incidence of gluten-related disorders (GRDs) continues to increase and its global prevalence is estimated affect to 5% of the population. s. Celiac disease (CD), Dermatitis Herpetiformis (DH), Gluten Ataxia (GA), wheat allergy (WA), and Non-Celiac Gluten Sensitivity (NCGS) are the five major GRD...

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Έκδοση: MDPI - Multidisciplinary Digital Publishing Institute 2021
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collection Directory of Open Access Books
description The incidence of gluten-related disorders (GRDs) continues to increase and its global prevalence is estimated affect to 5% of the population. s. Celiac disease (CD), Dermatitis Herpetiformis (DH), Gluten Ataxia (GA), wheat allergy (WA), and Non-Celiac Gluten Sensitivity (NCGS) are the five major GRDs that present with a wide range of clinical manifestations. They are manifested by symptoms of gastrointestinal tract disorders, as well as hematological, dermatological endocrinological, gynecological, rheumatological and nervous system. NCGS is a term that is used to describe individuals who are not affected by celiac disease or wheat allergy, yet they have intestinal and/or extra-intestinal symptoms related to gluten ingestion with improvement of their symptoms upon withdrawing gluten from their diet. It is believed that represents some heterogeneous groups with different subgroups characterized by different etiologies, clinical histories and clinical courses. There also appears to be an overlap between NCGS and irritable bowel syndrome (IBS). There is a need for establishing strict criteria for diagnosing NCGS. The absence of validated biomarkers remains a significant limitation for research studies on NCGS. New evidence shows that a gluten-free diet may be beneficial for some patients with gastrointestinal symptoms, such as those symptoms commonly found in patients with IBS.
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spelling doab-20.500.12854ir-692802024-03-31T13:09:57Z Advances in Celiac Disease Rodrigo, Luis celiac disease children HLA-DQ prevalence Asia wheat gluten non-celiac gluten-sensitivity diagnosis dermatitis herpetiformis anti-tTG anti-DGP AAA AGA IL-17A HLA-DQB1*02 screening first-degree relatives non-celiac gluten sensitivity irritable bowel disease FODMAP wheat allergy vitamin B12 iron folic acid vitamin D long-term GFD therapy (LTGFD) LTGFD with good compliance (LTGFDWGC) anemia lymphoma IgA deficiency gut enteropathy gluten-free diet level of evidences gluten-related disorders NCGS self-report survey studies n/a thema EDItEUR::M Medicine and Nursing The incidence of gluten-related disorders (GRDs) continues to increase and its global prevalence is estimated affect to 5% of the population. s. Celiac disease (CD), Dermatitis Herpetiformis (DH), Gluten Ataxia (GA), wheat allergy (WA), and Non-Celiac Gluten Sensitivity (NCGS) are the five major GRDs that present with a wide range of clinical manifestations. They are manifested by symptoms of gastrointestinal tract disorders, as well as hematological, dermatological endocrinological, gynecological, rheumatological and nervous system. NCGS is a term that is used to describe individuals who are not affected by celiac disease or wheat allergy, yet they have intestinal and/or extra-intestinal symptoms related to gluten ingestion with improvement of their symptoms upon withdrawing gluten from their diet. It is believed that represents some heterogeneous groups with different subgroups characterized by different etiologies, clinical histories and clinical courses. There also appears to be an overlap between NCGS and irritable bowel syndrome (IBS). There is a need for establishing strict criteria for diagnosing NCGS. The absence of validated biomarkers remains a significant limitation for research studies on NCGS. New evidence shows that a gluten-free diet may be beneficial for some patients with gastrointestinal symptoms, such as those symptoms commonly found in patients with IBS. 2021-05-01T15:45:42Z 2021-05-01T15:45:42Z 2020 book ONIX_20210501_9783039433841_1026 9783039433841 9783039433858 https://directory.doabooks.org/handle/20.500.12854/69280 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3070 https://mdpi.com/books/pdfview/book/3070 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-385-8 10.3390/books978-3-03943-385-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039433841 9783039433858 128 Basel, Switzerland open access
spellingShingle celiac disease
children
HLA-DQ
prevalence
Asia
wheat
gluten
non-celiac gluten-sensitivity
diagnosis
dermatitis herpetiformis
anti-tTG
anti-DGP
AAA
AGA
IL-17A
HLA-DQB1*02
screening
first-degree relatives
non-celiac gluten sensitivity
irritable bowel disease
FODMAP
wheat allergy
vitamin B12
iron
folic acid
vitamin D
long-term GFD therapy (LTGFD)
LTGFD with good compliance (LTGFDWGC)
anemia
lymphoma
IgA deficiency
gut
enteropathy
gluten-free diet
level of evidences
gluten-related disorders
NCGS
self-report
survey studies
n/a
thema EDItEUR::M Medicine and Nursing
Advances in Celiac Disease
title Advances in Celiac Disease
title_full Advances in Celiac Disease
title_fullStr Advances in Celiac Disease
title_full_unstemmed Advances in Celiac Disease
title_short Advances in Celiac Disease
title_sort advances in celiac disease
topic celiac disease
children
HLA-DQ
prevalence
Asia
wheat
gluten
non-celiac gluten-sensitivity
diagnosis
dermatitis herpetiformis
anti-tTG
anti-DGP
AAA
AGA
IL-17A
HLA-DQB1*02
screening
first-degree relatives
non-celiac gluten sensitivity
irritable bowel disease
FODMAP
wheat allergy
vitamin B12
iron
folic acid
vitamin D
long-term GFD therapy (LTGFD)
LTGFD with good compliance (LTGFDWGC)
anemia
lymphoma
IgA deficiency
gut
enteropathy
gluten-free diet
level of evidences
gluten-related disorders
NCGS
self-report
survey studies
n/a
thema EDItEUR::M Medicine and Nursing
topic_facet celiac disease
children
HLA-DQ
prevalence
Asia
wheat
gluten
non-celiac gluten-sensitivity
diagnosis
dermatitis herpetiformis
anti-tTG
anti-DGP
AAA
AGA
IL-17A
HLA-DQB1*02
screening
first-degree relatives
non-celiac gluten sensitivity
irritable bowel disease
FODMAP
wheat allergy
vitamin B12
iron
folic acid
vitamin D
long-term GFD therapy (LTGFD)
LTGFD with good compliance (LTGFDWGC)
anemia
lymphoma
IgA deficiency
gut
enteropathy
gluten-free diet
level of evidences
gluten-related disorders
NCGS
self-report
survey studies
n/a
thema EDItEUR::M Medicine and Nursing
url ONIX_20210501_9783039433841_1026