The Structural and Functional Study of Efflux Pumps Belonging to the RND Transporters Family from Gram-Negative Bacteria

Antimicrobial-resistant bacterial infections are a major and costly public health concern. Several pathogens are already pan-resistant, representing a major cause of mortality in patients suffering from nosocomial infections. Drug efflux pumps, which remove compounds from the bacterial cell, thereby...

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Dades bibliogràfiques
Format:	Online
Idioma:	anglès
Publicat:	MDPI - Multidisciplinary Digital Publishing Institute 2022
Matèries:	MdtF (YhiV) multidrug resistance RND-type efflux pump dye accumulation real-time efflux pathogens RND evolution efflux pump adaptation Aliarcobacter butzleri RND efflux pumps virulence resistance RND pump dominant negative effect assembly protein-protein interaction mutation drug resistance cystic fibrosis prevalence of efflux resistance mechanisms hospital acquired infections antibiotic resistance allostery antimicrobial resistance conformational changes energetic transition gram-negative bacteria pump activation n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
Accés en línia:	ONIX_20220506_9783036539461_112
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The Structural and Functional Study of Efflux Pumps Belonging to the RND Transporters Family from Gram-Negative Bacteria

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