Chapter Patient-generated evidence in Epidermolysis Bullosa (EB): Development of a questionnaire to assess the Quality of Life

Epidermolysis Bullosa (EB) is a group of genetic conditions that cause fragile and blistering skin. Although there are different types of EB, which differ in severity, their signs and symptoms overlap. As a result of this disorder, patients face an unbearable burden in their lives, and their Quality...

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Egile Nagusiak: Pilo, Cinzia, Benedan, Laura, El Hachem, May, Galeone, Carlotta, Mariani, Paolo, Tadini, Gianluca
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Argitaratua: Firenze University Press 2022
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author Pilo, Cinzia
Benedan, Laura
El Hachem, May
Galeone, Carlotta
Mariani, Paolo
Tadini, Gianluca
author_browse Benedan, Laura
El Hachem, May
Galeone, Carlotta
Mariani, Paolo
Pilo, Cinzia
Tadini, Gianluca
author_facet Pilo, Cinzia
Benedan, Laura
El Hachem, May
Galeone, Carlotta
Mariani, Paolo
Tadini, Gianluca
author_sort Pilo, Cinzia
collection Directory of Open Access Books
description Epidermolysis Bullosa (EB) is a group of genetic conditions that cause fragile and blistering skin. Although there are different types of EB, which differ in severity, their signs and symptoms overlap. As a result of this disorder, patients face an unbearable burden in their lives, and their Quality of Life (QoL) is negatively affected at every life cycle stage. Nevertheless, the assessment of the quality of life of these patients is scanty. This project aims to develop a patient-centered questionnaire to assess the QoL of EB patients. This tool will be a valid aid for clinicians to understand patients better and identify the areas that need more attention; moreover, it will allow them to follow the patients over time and evaluate the impact of any treatments. The methodological process to develop the questionnaire consisted of two phases: firstly, a critical review of scientific literature was performed; secondly, a pseudo-Delphi study was carried out. A multidisciplinary panel (including patients, caregivers, and clinicians) actively participated in round tables to discuss the main areas of interest. Starting from this initial set of areas and through the repetition of Delphi (up to three rounds), a gradual refinement of the statements was carried out to define a list of items to be included in an easy-to-use but meaningful questionnaire. The final patient-centered questionnaire is thus able to measure the QoL beyond the physical symptoms and the clinical evolution of the disease, encompassing functional autonomy, psycho-emotional state, social relations and the working field.
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spelling doab-20.500.12854ir-924792025-08-13T13:42:37Z Chapter Patient-generated evidence in Epidermolysis Bullosa (EB): Development of a questionnaire to assess the Quality of Life Pilo, Cinzia Benedan, Laura El Hachem, May Galeone, Carlotta Mariani, Paolo Tadini, Gianluca Epidermolysis Bullosa Patient-centered approach Quality of Life Pseudo-Delphi thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology::JHBC Social research and statistics thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology::JHBC Social research and statistics Epidermolysis Bullosa (EB) is a group of genetic conditions that cause fragile and blistering skin. Although there are different types of EB, which differ in severity, their signs and symptoms overlap. As a result of this disorder, patients face an unbearable burden in their lives, and their Quality of Life (QoL) is negatively affected at every life cycle stage. Nevertheless, the assessment of the quality of life of these patients is scanty. This project aims to develop a patient-centered questionnaire to assess the QoL of EB patients. This tool will be a valid aid for clinicians to understand patients better and identify the areas that need more attention; moreover, it will allow them to follow the patients over time and evaluate the impact of any treatments. The methodological process to develop the questionnaire consisted of two phases: firstly, a critical review of scientific literature was performed; secondly, a pseudo-Delphi study was carried out. A multidisciplinary panel (including patients, caregivers, and clinicians) actively participated in round tables to discuss the main areas of interest. Starting from this initial set of areas and through the repetition of Delphi (up to three rounds), a gradual refinement of the statements was carried out to define a list of items to be included in an easy-to-use but meaningful questionnaire. The final patient-centered questionnaire is thus able to measure the QoL beyond the physical symptoms and the clinical evolution of the disease, encompassing functional autonomy, psycho-emotional state, social relations and the working field. 2022-09-22T04:23:26Z 2022-09-22T04:23:26Z 2022-09-15T20:05:49Z 2021 chapter ONIX_20220915_9788855184618_26 2704-5846 https://library.oapen.org/handle/20.500.12657/58230 9788855184618 https://directory.doabooks.org/handle/20.500.12854/92479 eng Proceedings e report open access image/jpeg image/jpeg Attribution 4.0 International Attribution 4.0 International https://library.oapen.org/bitstream/20.500.12657/58230/1/978-88-5518-461-8_38.pdf https://library.oapen.org/bitstream/20.500.12657/58230/1/978-88-5518-461-8_38.pdf Firenze University Press 10.36253/978-88-5518-461-8.38 10.36253/978-88-5518-461-8.38 2ec4474d-93b1-4cfa-b313-9c6019b51b1a 9788855184618 5 Florence open access
spellingShingle Epidermolysis Bullosa
Patient-centered approach
Quality of Life
Pseudo-Delphi
thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology::JHBC Social research and statistics
thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology::JHBC Social research and statistics
Pilo, Cinzia
Benedan, Laura
El Hachem, May
Galeone, Carlotta
Mariani, Paolo
Tadini, Gianluca
Chapter Patient-generated evidence in Epidermolysis Bullosa (EB): Development of a questionnaire to assess the Quality of Life
title Chapter Patient-generated evidence in Epidermolysis Bullosa (EB): Development of a questionnaire to assess the Quality of Life
title_full Chapter Patient-generated evidence in Epidermolysis Bullosa (EB): Development of a questionnaire to assess the Quality of Life
title_fullStr Chapter Patient-generated evidence in Epidermolysis Bullosa (EB): Development of a questionnaire to assess the Quality of Life
title_full_unstemmed Chapter Patient-generated evidence in Epidermolysis Bullosa (EB): Development of a questionnaire to assess the Quality of Life
title_short Chapter Patient-generated evidence in Epidermolysis Bullosa (EB): Development of a questionnaire to assess the Quality of Life
title_sort chapter patient generated evidence in epidermolysis bullosa eb development of a questionnaire to assess the quality of life
topic Epidermolysis Bullosa
Patient-centered approach
Quality of Life
Pseudo-Delphi
thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology::JHBC Social research and statistics
thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology::JHBC Social research and statistics
topic_facet Epidermolysis Bullosa
Patient-centered approach
Quality of Life
Pseudo-Delphi
thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology::JHBC Social research and statistics
thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology::JHBC Social research and statistics
url ONIX_20220915_9788855184618_26
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