High-Fat High-Saturated Diet
Dietary fat quality is a crucial determinant of several physiological, biochemical and molecular processes in the body, tissues and cells. As a source of energy, Fatty Acids (FA) are mainly stored in fat cells and within lipid droplets (LD) in oxidative and steroidogenic tissues, but significant amo...
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| Формат: | Online |
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| Язык: | английский |
| Опубликовано: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Предметы: | |
| Online-ссылка: | ONIX_20221117_9783036553047_49 |
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Нет меток, Требуется 1-ая метка записи!
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| _version_ | 1869516090379337728 |
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| collection | Directory of Open Access Books |
| description | Dietary fat quality is a crucial determinant of several physiological, biochemical and molecular processes in the body, tissues and cells. As a source of energy, Fatty Acids (FA) are mainly stored in fat cells and within lipid droplets (LD) in oxidative and steroidogenic tissues, but significant amounts are also found in cell membranes where their structural role is crucial for membrane protein functions and the control of cellular functions. Differential effects have been identified between different types FA on inflammatory and metabolic diseases during obesity or in response to physical exercise and chronic diseases. The most recent dietary guidelines advise that lipids should represent 35% of the daily energy intake in order to prevent deleterious effects of high glycaemic index carbohydrates and deficiency in essential fatty acids. Hence, the prevalence of obesity could rise dramatically despite a fall in total fat intake. Advice is more focused on the improvement of the quality of fat than on the reduction of total fat intake. Dietary fat sources provide a mixture of saturated FA (SFA), monounsaturated FA (MUFA) and polyunsaturated FA (PUFA). Most institutional dietary guidelines claim that the consumption of SFA should be limited to the expense of MUFA and PUFA as a nutritional strategy for the prevention of chronic diseases. The role of dietary SFA and MUFA in cardiometabolic risk remains controversial in the scientific community. This special issue was proposed to publish articles that bring new elements into the topic by collecting recent advances for students and professionals involved in lipid and health. |
| format | Online |
| id | doab-20.500.12854ir-93792 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-937922024-03-28T03:30:45Z High-Fat High-Saturated Diet Capel, Frederic adipose tissue caloric restriction high-fat diet nonhuman primates obesity transcriptome western-style diet olive oil aminopeptidase activity renin–angiotensin-system heart fatty acids cell membrane sphingolipids phospholipids polyunsaturated fatty acids cholesterol insulin signaling mitochondria brain inflammation JNK insulin receptor genomics microvascular dementia hyperlipidemia Western diet males preadipocyte TLR4 free fatty acid ageing muscle mass dietary fats macronutrients isocaloric substitution muscle strength physical activity metabolic syndrome metabolism type 2 diabetes insulin resistance rodent models of type 2 diabetes microRNA liver omega 3 fatty acids high fat diet intermittent fasting GFAP proteomics saturated fatty acids cardiac muscle omega-6/omega-3 ratio monounsaturated fatty acids purified high-fat diets endothelial dysfunction nitric oxide vascular remodeling arterial stiffness collagen fiber inulin lipid microbiota HFD SFA omega-3 PUFA omega-6 PUFA nutriproteomics 2DE MALDI TOF/TOF thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society Dietary fat quality is a crucial determinant of several physiological, biochemical and molecular processes in the body, tissues and cells. As a source of energy, Fatty Acids (FA) are mainly stored in fat cells and within lipid droplets (LD) in oxidative and steroidogenic tissues, but significant amounts are also found in cell membranes where their structural role is crucial for membrane protein functions and the control of cellular functions. Differential effects have been identified between different types FA on inflammatory and metabolic diseases during obesity or in response to physical exercise and chronic diseases. The most recent dietary guidelines advise that lipids should represent 35% of the daily energy intake in order to prevent deleterious effects of high glycaemic index carbohydrates and deficiency in essential fatty acids. Hence, the prevalence of obesity could rise dramatically despite a fall in total fat intake. Advice is more focused on the improvement of the quality of fat than on the reduction of total fat intake. Dietary fat sources provide a mixture of saturated FA (SFA), monounsaturated FA (MUFA) and polyunsaturated FA (PUFA). Most institutional dietary guidelines claim that the consumption of SFA should be limited to the expense of MUFA and PUFA as a nutritional strategy for the prevention of chronic diseases. The role of dietary SFA and MUFA in cardiometabolic risk remains controversial in the scientific community. This special issue was proposed to publish articles that bring new elements into the topic by collecting recent advances for students and professionals involved in lipid and health. 2022-11-17T16:24:55Z 2022-11-17T16:24:55Z 2022 book ONIX_20221117_9783036553047_49 9783036553047 9783036553030 https://directory.doabooks.org/handle/20.500.12854/93792 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/6221 https://mdpi.com/books/pdfview/book/6221 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-5304-7 10.3390/books978-3-0365-5304-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036553047 9783036553030 284 Basel open access |
| spellingShingle | adipose tissue caloric restriction high-fat diet nonhuman primates obesity transcriptome western-style diet olive oil aminopeptidase activity renin–angiotensin-system heart fatty acids cell membrane sphingolipids phospholipids polyunsaturated fatty acids cholesterol insulin signaling mitochondria brain inflammation JNK insulin receptor genomics microvascular dementia hyperlipidemia Western diet males preadipocyte TLR4 free fatty acid ageing muscle mass dietary fats macronutrients isocaloric substitution muscle strength physical activity metabolic syndrome metabolism type 2 diabetes insulin resistance rodent models of type 2 diabetes microRNA liver omega 3 fatty acids high fat diet intermittent fasting GFAP proteomics saturated fatty acids cardiac muscle omega-6/omega-3 ratio monounsaturated fatty acids purified high-fat diets endothelial dysfunction nitric oxide vascular remodeling arterial stiffness collagen fiber inulin lipid microbiota HFD SFA omega-3 PUFA omega-6 PUFA nutriproteomics 2DE MALDI TOF/TOF thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society High-Fat High-Saturated Diet |
| title | High-Fat High-Saturated Diet |
| title_full | High-Fat High-Saturated Diet |
| title_fullStr | High-Fat High-Saturated Diet |
| title_full_unstemmed | High-Fat High-Saturated Diet |
| title_short | High-Fat High-Saturated Diet |
| title_sort | high fat high saturated diet |
| topic | adipose tissue caloric restriction high-fat diet nonhuman primates obesity transcriptome western-style diet olive oil aminopeptidase activity renin–angiotensin-system heart fatty acids cell membrane sphingolipids phospholipids polyunsaturated fatty acids cholesterol insulin signaling mitochondria brain inflammation JNK insulin receptor genomics microvascular dementia hyperlipidemia Western diet males preadipocyte TLR4 free fatty acid ageing muscle mass dietary fats macronutrients isocaloric substitution muscle strength physical activity metabolic syndrome metabolism type 2 diabetes insulin resistance rodent models of type 2 diabetes microRNA liver omega 3 fatty acids high fat diet intermittent fasting GFAP proteomics saturated fatty acids cardiac muscle omega-6/omega-3 ratio monounsaturated fatty acids purified high-fat diets endothelial dysfunction nitric oxide vascular remodeling arterial stiffness collagen fiber inulin lipid microbiota HFD SFA omega-3 PUFA omega-6 PUFA nutriproteomics 2DE MALDI TOF/TOF thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society |
| topic_facet | adipose tissue caloric restriction high-fat diet nonhuman primates obesity transcriptome western-style diet olive oil aminopeptidase activity renin–angiotensin-system heart fatty acids cell membrane sphingolipids phospholipids polyunsaturated fatty acids cholesterol insulin signaling mitochondria brain inflammation JNK insulin receptor genomics microvascular dementia hyperlipidemia Western diet males preadipocyte TLR4 free fatty acid ageing muscle mass dietary fats macronutrients isocaloric substitution muscle strength physical activity metabolic syndrome metabolism type 2 diabetes insulin resistance rodent models of type 2 diabetes microRNA liver omega 3 fatty acids high fat diet intermittent fasting GFAP proteomics saturated fatty acids cardiac muscle omega-6/omega-3 ratio monounsaturated fatty acids purified high-fat diets endothelial dysfunction nitric oxide vascular remodeling arterial stiffness collagen fiber inulin lipid microbiota HFD SFA omega-3 PUFA omega-6 PUFA nutriproteomics 2DE MALDI TOF/TOF thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society |
| url | ONIX_20221117_9783036553047_49 |