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Advanced Blood-Brain Barrier Drug Delivery

Advanced Blood-Brain Barrier Drug Delivery is a reprint with a summary editorial, followed by 16 chapters that cover five areas of brain drug delivery, including receptor-mediated transport (RMT), carrier-mediated transport (CMT), active efflux transport (AET), Trojan horse lipid nanoparticles (LNP)...

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Gardado en:
Formato: Online
Idioma:inglés
Publicado: MDPI - Multidisciplinary Digital Publishing Institute 2023
Subjects:
blood–brain barrier (BBB)
brain drug delivery
prodrugs
solute carriers (SLCs)
lysosomal storage disease
neuronopathic mucopolysaccharidosis
blood–brain barrier
neurodegeneration
enzyme replacement therapy
receptor-mediated transcytosis
transferrin receptor
insulin receptor
endothelium
receptor-mediated transport
carrier-mediated transport
genetic engineering
IgG fusion proteins
nanoparticles
liposomes
TrkB
agonist antibody
variable new antigen receptor (VNAR)
neuroprotection
transferrin receptor 1 (TfR1)
blood-brain barrier (BBB)
6-OHDA
Parkinson’s disease
bispecific antibody
alpha-synuclein (αSYN)
Parkinson’s disease (PD)
immunotherapy
monoclonal antibody
transferrin receptor (TfR)
receptor-mediated transcytosis (RMT)
single domains antibody
IGF1R
neurotensin
protein-based therapy
lysosomal storage disorders
fusion proteins
Alzheimer’s disease
neurotrophic factors
decoy receptors
ATP-binding cassette transporters
drug delivery
ischemic stroke
SLC transporters
lipid nanoparticle
ssPalm
mRNA transfection
hCMEC/D3 cells
cell toxicity
SWATH-MS
translation
chaperonin-containing TCP-1
proton-coupled organic cation antiporter
photo-affinity labeling
proteomics
SWATH-MS (sequential window acquisition of all theoretical-mass spectra)
pharmacokinetics
compartmental models
physiologically based PK models
blood-brain barrier
antibody
cavernous sinus
BBB–peptide shuttle
brain delivery
solute carrier (SLC) transporters
amyotrophic lateral sclerosis (ALS)
NSC-34 cell lines
taurine transporter (Taut)
large amino acid transporter 1 (LAT1)
monocarboxylate transporters (MCTs)
organic cation transporters (OCTNs)
choline transporter-like protein-1 (CTL1)
TNF-α inhibitor
molecular Trojan horse
endosomal
liposome
nanoparticle
targeting
transferrin
n/a
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology
Acceso en liña:ONIX_20230202_9783036564173_130
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Summary:Advanced Blood-Brain Barrier Drug Delivery is a reprint with a summary editorial, followed by 16 chapters that cover five areas of brain drug delivery, including receptor-mediated transport (RMT), carrier-mediated transport (CMT), active efflux transport (AET), Trojan horse lipid nanoparticles (LNP), and in vivo methods for measurement of drug transport across the blood–brain barrier (BBB).

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