LC-MS/MS Method for Mycotoxin Analysis
Mycotoxins are secondary metabolites produced by some species of filamentous fungi belonging to Fusarium, Aspergillus, Penicillium, Claviceps and Alternaria genera. The biochemical significance of mycotoxins in fungal metabolism has not always been fully clarified; however, the main concern for myco...
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| פורמט: | Online |
| שפה: | אנגלית |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| גישה מקוונת: | 24891 |
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| _version_ | 1869523580699541504 |
|---|---|
| author | Aldo Laganà (Ed.) |
| author_browse | Aldo Laganà (Ed.) |
| author_facet | Aldo Laganà (Ed.) |
| author_sort | Aldo Laganà (Ed.) |
| collection | Directory of Open Access Books |
| description | Mycotoxins are secondary metabolites produced by some species of filamentous fungi belonging to Fusarium, Aspergillus, Penicillium, Claviceps and Alternaria genera. The biochemical significance of mycotoxins in fungal metabolism has not always been fully clarified; however, the main concern for mycotoxins is driven by the deleterious effects they can exert on human and animal health. Structurally, the mycotoxins currently known belong to heterogeneous chemical classes, therefore the toxic effects they can induce are highly diverse (e.g., cancerogenic and immunosuppressive effects). The main route of human exposure to mycotoxins is by intake of contaminated food, either directly from contaminated agricultural products, or indirectly from residues and metabolites present in foods of animal origin. Immunochemical methods are generally used for the fast screening of mycotoxin presence; however, for confirmation purposes, analytical methods based on high-performance liquid chromatography (LC) are preferred, especially when coupled with tandem mass spectrometry (MS/MS), which allows the determination of multiclass mycotoxins in a single analysis. Moreover, the technical innovations available in LC-MS/MS instrumentation are prompting its application to the monitoring of contaminants in food and feed. The aim of this paper collection, constituted by ten research articles and one review, is to provide the reader with an overview on the novelties and capabilities in LC-MS/MS-based multi-mycotoxin methods, also including the investigation of emerging and modified mycotoxins. |
| format | Online |
| id | doab-20.500.12854ir-51470 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-514702024-04-05T12:39:30Z LC-MS/MS Method for Mycotoxin Analysis Aldo Laganà (Ed.) QD1-999 Analytical methods Mycotoxin extraction from cereals Mycotoxins Cereal contamination LC-MS/MS: Multi-mycotoxin analysis thema EDItEUR::P Mathematics and Science::PN Chemistry Mycotoxins are secondary metabolites produced by some species of filamentous fungi belonging to Fusarium, Aspergillus, Penicillium, Claviceps and Alternaria genera. The biochemical significance of mycotoxins in fungal metabolism has not always been fully clarified; however, the main concern for mycotoxins is driven by the deleterious effects they can exert on human and animal health. Structurally, the mycotoxins currently known belong to heterogeneous chemical classes, therefore the toxic effects they can induce are highly diverse (e.g., cancerogenic and immunosuppressive effects). The main route of human exposure to mycotoxins is by intake of contaminated food, either directly from contaminated agricultural products, or indirectly from residues and metabolites present in foods of animal origin. Immunochemical methods are generally used for the fast screening of mycotoxin presence; however, for confirmation purposes, analytical methods based on high-performance liquid chromatography (LC) are preferred, especially when coupled with tandem mass spectrometry (MS/MS), which allows the determination of multiclass mycotoxins in a single analysis. Moreover, the technical innovations available in LC-MS/MS instrumentation are prompting its application to the monitoring of contaminants in food and feed. The aim of this paper collection, constituted by ten research articles and one review, is to provide the reader with an overview on the novelties and capabilities in LC-MS/MS-based multi-mycotoxin methods, also including the investigation of emerging and modified mycotoxins. 2021-02-11T17:29:53Z 2021-02-11T17:29:53Z 2017-12-22 11:28:33 2017 book 24891 9783038426073 9783038426066 https://directory.doabooks.org/handle/20.500.12854/51470 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International http://amzn.to/2kXUVc7 http://www.mdpi.com/books/pdfview/book/469 MDPI - Multidisciplinary Digital Publishing Institute 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038426073 9783038426066 VIII, 186 open access |
| spellingShingle | QD1-999 Analytical methods Mycotoxin extraction from cereals Mycotoxins Cereal contamination LC-MS/MS: Multi-mycotoxin analysis thema EDItEUR::P Mathematics and Science::PN Chemistry Aldo Laganà (Ed.) LC-MS/MS Method for Mycotoxin Analysis |
| title | LC-MS/MS Method for Mycotoxin Analysis |
| title_full | LC-MS/MS Method for Mycotoxin Analysis |
| title_fullStr | LC-MS/MS Method for Mycotoxin Analysis |
| title_full_unstemmed | LC-MS/MS Method for Mycotoxin Analysis |
| title_short | LC-MS/MS Method for Mycotoxin Analysis |
| title_sort | lc ms ms method for mycotoxin analysis |
| topic | QD1-999 Analytical methods Mycotoxin extraction from cereals Mycotoxins Cereal contamination LC-MS/MS: Multi-mycotoxin analysis thema EDItEUR::P Mathematics and Science::PN Chemistry |
| topic_facet | QD1-999 Analytical methods Mycotoxin extraction from cereals Mycotoxins Cereal contamination LC-MS/MS: Multi-mycotoxin analysis thema EDItEUR::P Mathematics and Science::PN Chemistry |
| url | 24891 |
| work_keys_str_mv | AT aldolaganaed lcmsmsmethodformycotoxinanalysis |